同种异体骨移植治疗四肢良性骨肿瘤术后骨缺损疗效的观察  

A Comparative Study on Allogeneic Bone Graft for the Treatment of Bone Defect after Resection of Benign Bone Tumor in the Long Bone of Extremities

作　　者：康献刚 赵智远 吴旭芝 沈庆欣 武密山[2] 

机构地区：[1]河北邢台医专第二附属医院骨科,河北邢台054000 [2]河北医科大学第一医院骨科,河北石家庄050030

出　　处：《医学临床研究》2015年第12期2289-2291,共3页Journal of Clinical Research

基　　金：国家自然科学基金（81073074）

摘　　要：【目的】观察比较在治疗良性骨肿瘤术后导致的骨缺损中自体骨移植与同种异体骨移植的临床效果。【方法】对2009年7月到2013年7月于本院接受自体骨移植的33个病例和同种异体骨移植的40个病例进行回顾性分析，随访时间为12-36个月。通过随访期的影像学检查以及临床效果，比较两组的愈合速度以及愈合率。【结果】自体骨移植和同种异体骨移植病例初步愈合率均为100％，自体骨移植与同种异体骨移植平均愈合时间分别为（16．4±3．4）周和（17．8±3．2）周（P〉0．05）。自体骨移植和同种异体骨移植术后平均愈合评分分别为（2．5±0．3）分和（2．4±0．5）分（P〉0．05），自体骨移植和同种异体骨移植术后并发症发生率为15．2％和17．5％（P〉0．05）。【结论】应用同种异体骨和自体骨移植重建四肢长骨缺损，均能获得满意效果且疗效相似。[Objective]To investigate the clinical effects in the use of allogeneic bone transplantation combined with autogeneic bone transplantation after the resection of a benign bone tumor, [Methods]The patients who received allogeneic bone and autogeneic bone transplantation respectively in our hospital from July 2009 to July 2013 were divided into 2 groups.The period of follow-up was 12 to 36 months. Based on imaging and clinical results during the follow-up, the healing speeds and healing rates after bone transplantation between the 2 groups were compared. [Resuits]Both initial healing rates of autogeneic bone transplantation and allogeneic bone transplantation were 100 %. The mean healing times of autogeneic bone transplantation and allogeneic bone transplantation were （16.4 ± 3.4） weeks and （17.8±3.2） weeks（ P 〈0.05）;the mean healing scores were （2.5±0.3） points and （2.4±0.5） points（ P 〈0.05）. The mean.rates of the postoperative complications of autogeneic bone transplantation and allogeneic bone transplantation were 15.2% and 17.5% （ P〈0.05）. [Conclusion]Reconstruction using bone autograft and allograft for long bone defects have similar clinical curative effect.

关 键 词：骨肿瘤/外科学 手术后并发症/外科学 骨疾病/外科学 骨移植 四肢 移植 同种 

分 类 号：R738.1[医药卫生—肿瘤]