动脉栓塞治疗妊娠滋养细胞肿瘤6例临床分析  

Analysis of treatment and prognosis for six cases of gestational trophoblastic neoplasia by arterial embolizastion

作　　者：乐晓妮[1] 孙莉[2] 陆佳琦[1] 奚美丽[1] 张国福[3] 鹿欣[1] 

机构地区：[1]复旦大学附属妇产科医院妇瘤科,上海200011 [2]复旦大学附属妇产科医院超声科,上海200011 [3]复旦大学附属妇产科医院放射科,上海200011

出　　处：《现代妇产科进展》2015年第11期840-843,共4页Progress in Obstetrics and Gynecology

摘　　要：目的：探讨妊娠滋养细胞肿瘤（ GTN ）患者行动脉栓塞术治疗的方法及疗效. 方法：回顾分析2008年1月至2014年12月在复旦大学附属妇产科医院因大出血或子宫动静脉瘘而行子宫或股动脉栓塞术治疗的6例妊娠滋养细胞肿瘤患者的临床资料.结果：6例GTN患者中有转移病灶伴大出血者3例,超声检查发现子宫动静脉瘘3例;入院即刻行栓塞术者4例,化疗后行栓塞术者2例;6例患者均栓塞成功. 栓塞后接受手术治疗3例. 所有患者均采用单药或多药联合化疗平均9. 12 个疗程（6 ~11 疗程）,5 例（83. 3%）患者完全缓解. 结论：有出现转移病灶、子宫动静脉瘘时采用动脉栓塞术及时安全有效地控制病情,为全身化疗提供治疗机会. 栓塞术后全身化疗仍是GTN的主要治疗方法.Objective：To analyze the treatment and prognosis of six patients with gesta-tional tropholastic neoplasia （ GTN） by emergency arterial embolizastion. Methods：Treatment and prognosis of six patients with gestational tropholastic neoplasia by emergency arterial embo-lizastion from Jun 2008 to Dec. 2014 at Obstetrics and Gynecology Hospital of Fudan University were study retrospectively . Results：Six cases with GTN had arterial embolizastion. There had a-cute abnormal bleeding from metastatic lesions, three had uterine arteriovenous malformation （ AVM） . Four cases were given arterial embolizastion immediately and two cases were used after chemotherapy. All cases were successful in controlling the bleeding,which operated three cases. All cases were received 9 . 12 courses of simple or multi drugs chemotherapy （ range 6~11 ） . Five cases （ 83. 3%） were achieved complete remission. Conclusions：Arterial embolizastion can controlled acute abnormal blood with metastasis and uterine AVM. It is safety method and effectively control the disease progression, which to get the chance for chemotherapy. Chemo-therapy is the main strategy for patients with GTN after arterial embolizastion.

关 键 词：妊娠滋养细胞肿瘤 动脉栓塞术 治疗 

分 类 号：R737.33[医药卫生—肿瘤]