我校新开教学实验“荷包牡丹碱的分离纯化”的设计  

A new teaching experiment that the design of isolation and purification of dicentrine in our school

作　　者：韦琨[1] 蔡乐[1] 刘金[1] 周皓[1] 曹秋娥[1] 

机构地区：[1]云南大学化学科学与工程学院,云南昆明650091

出　　处：《中国医药导报》2016年第2期167-169,共3页China Medical Herald

基　　金：云南省高校本科教学质量与教学改革工程项目(2013)

摘　　要：天然药物化学是药学专业的重要的专业必修课程,其配套实验课程设计对于该课程的教学非常重要。云南大学化学科学与工程学院新开了一个天然药物化学教学实验——荷包牡丹碱的分离纯化。本实验通过甲醇超声提取、硅胶柱层析划段和甲醇重结晶三个步骤,即可从云南传统中药地不容中获得纯度较高的荷包牡丹碱。本实验简便、高效且易于操作,适合用于制药工程专业本科生的实验教学。Chemistry of natural medicine is an important compulsory course for pharmaceutical specialty and the corresponding experiment course is also very important. A new teaching experiment for chemistry of natural medicine-- isolation and purification of dicentrine is developed in School of Chemical Science and Technology, Yunnan University. In this experiment, pure dicentrine can be obtained from Stephania epigaea according to methanol ultrasonic extraction, silica gel column chromatography, and methanol recrystallization. This experiment is convenient, effective, and suitable to be a teaching experiment for the undergraduate of pharmaceutical engineering.

关 键 词：荷包牡丹碱 提取分离 天然药物化学 制药工程专业 

分 类 号：G642.0[文化科学—高等教育学]