瘤体尿素注射联合手术切除治疗足部海绵状血管瘤62例临床分析  

Intralesional injection of urea combined with surgical resection for foot cavernous hemangioma

作　　者：郭晓楠[1] 董长宪[1] 马玉春[1] 朱晓爽[1] 

机构地区：[1]郑州大学人民医院河南省人民医院血管瘤科,郑州450003

出　　处：《中华实用诊断与治疗杂志》2016年第1期58-59,共2页Journal of Chinese Practical Diagnosis and Therapy

基　　金：2014年河南省科技厅科技攻关项目(142102310080)

摘　　要：目的 探讨瘤体内尿素注射联合手术切除治疗足部海绵状血管瘤的临床效果。方法 62例足部海绵状血管瘤患者均行瘤体尿素注射＋手术切除治疗,术后随访24~48个月,观察局部症状、关节活动改善情况及复发率。结果 62例中行一期根治性切除术41例,分期根治性手术17例,减瘤手术4例,同期行肌腱延长/黏连松解术11例;术后局部疼痛缓解率为80.95%（17/21）,关节活动度改善率为72.73%（8/11）。术后6~12个月复发5例（一期根治性切除术3例,分期根治性手术2例）,复发率为8.06%,术后〉12~48个月无新增复发患者。结论 瘤体内尿素注射后行手术治疗可降低手术难度及风险,治疗足部海绵状血管瘤疗效确切。Objective To summarize and evaluate the therapeutic effect of intralesional injection of urea combined with surgical resection for foot cavernous hemangioma. Methods Sixty-two cases of foot cavernous hemangioma received surgical resection after intralesional injection of urea. All patients were followed up for 24 to 48 months to observe local symptoms, motion of joint and recurrence rate. Results Forty-one patients underwent one-stage complete resection, 17 underwent two-stage operation, 4 underwent partial resection to release clinical symptoms, and 11 received tendon lengthening/adhesiolysis in synchronization. The local pain relieving rate was 80. 95% （17/21） and the joint motion improving rate was 72.73 % （8/11） after operation. The 6- to 12-month follow up survey found recurrence in 5 patients, including 3 patients after one-stage operation and 2 after two-stage operation, with the recurrent rate of 8. 06%. No recurrence was found in 12 to 48 months after operation. Conclusion Intralesional injection of urea may reduce the difficulty and risk of the surgery, and is effective and safe for foot cavernous hemangioma.

关 键 词：海绵状血管瘤 静脉畸形 手术 尿素 

分 类 号：R739.96[医药卫生—肿瘤]