益气健脾化积方对胃癌化疗增效的理论机制探讨  

Discussion on the theoretical mechanism of the chemotherapeutic synergy of Replenishing Qi to Invigorate the Spleen and Relieve Stasis Decoction for gastric cancer

作　　者：李堃[1] 林安安[1] 朱方石 

机构地区：[1]南京中医药大学第一临床医学院,江苏南京210023 [2]南京中医药大学附属中西医结合医院中西医结合临床研究室,江苏南京210028

出　　处：《中国医药导报》2016年第1期95-97,共3页China Medical Herald

基　　金：国家中医临床研究基地业务建设科研专项(JDZX2012089)

摘　　要：本文就益气健脾化积方对胃癌化疗的增效作用从方剂组方结构理论及意义、化疗的证机变化与"方证相应"的证治立法基础以及方剂所含药物抗癌药理作用等三个方面进行了理论分析,认为该方对胃癌化疗发挥的增效作用是建立在中医的理、法、方、药的理论基础之上,且与辨证用药的传统中药功效理论及所含药物的抗癌药理作用相关。This article discusses and analyzes about the theoretical mechanism of the chemotherapeutic synergy of Replenishing Qi to Invigorate the Spleen and Relieve Stasis Decoction to the patients with gastric cancer,which is from the theory and significance of prescription structure,the legislative basis for treatment card machine change chemotherapy and ＂corresponding of prescription and syndrome＂,as well as the pharmacological effects of drugs in the prescription,it is thought that the chemotherapeutic synergy on gastric cancer is based on the TCM theory,methods,prescriptions and medicine,and related to the traditional Chinese medicine efficacy theory for syndrome differentiation and anticancer pharmacological effects of the drug.

关 键 词：益气健脾化积方 胃癌 化疗增效 理论机制 

分 类 号：R735.7[医药卫生—肿瘤]