轻症卒中的溶栓治疗  

Thrombolyfic therapy in patients with mild stroke

作　　者：林亚楠[1] 王玉[1] 孙晓培[1] 

机构地区：[1]大连医科大学附属第一医院神经内科,116011

出　　处：《国际脑血管病杂志》2015年第11期849-853,共5页International Journal of Cerebrovascular Diseases

摘　　要：轻症卒中是指神经功能轻度缺损的缺血性卒中，近年来其发病率逐渐升高。然而，目前对轻症卒中尚无规范的定义，是否对其行溶栓治疗也存在很大争议。传统观点认为轻症卒中患者不应行静脉溶栓治疗，不过，许多研究表明未接受溶栓治疗的轻症卒中患者短期和中期转归较差，并且许多轻症卒中患者可受益于溶栓治疗。文章对近年来有关轻症卒中定义及溶栓治疗的临床研究进行总结，希望能给临床医生提供参考，以便做出更好的临床决策。Mild stroke refers to ischemic stroke with mild neurological defects. In recent years, its incidence rate has increased gradually. However, there is no standardized definition for mild stroke, and there is a great controversy about whether to conduct thrombolytic therapy for mild stroke. The conventional wisdom holds that the patients with mild stroke should not be treated with intravenous thrombolysis; however, many studies have indicated that the short-term and medium-term outcomes are poor in patients with mild stroke without receiving thrombolytic therapy, and many patients with mild stroke may benefit from thrombolytic therapy. This article summarizes about the definition of mild stroke and the clinical studies of thrombolytic therapy in recent years, hoping to provide reference for clinicians in order to make better clinical decisions.

关 键 词：卒中 脑缺血 血栓溶解疗法 组织型纤溶酶原激活物 

分 类 号：R743.3[医药卫生—神经病学与精神病学]