大脑前动脉A1段发育不良与前交通动脉瘤发生率的MRA诊断  

Magnetic Resonance Angiography in Assessment of A1 Segment Hypoplasia and Acom A Aneurysm

作　　者：陈豪[1] 赵江民[1] 吴利忠[1] 钱海珊[1] 李克[2] 

机构地区：[1]上海交通大学医学院附属第三人民医院医学影像科 [2]复旦大学附属华山医院放射科

出　　处：《中国医学计算机成像杂志》2015年第6期519-523,共5页Chinese Computed Medical Imaging

基　　金：上海市科委科技创新行动计划重点项目No.10411953400~~

摘　　要：目的:通过3D-TOF-MRA调查人群中大脑前动脉A1段发育不良的发生率以及其与前交通动脉瘤发生率的相关性。方法:2009年1月至2012年12月8013例患者行3.0T 3D-TOF-MRA检查并纳入研究,以容积重建(VR)及轴位原始图像作为诊断标准,对大脑前动脉A1段发育不良和前交通动脉瘤的发生率及发生部位进行统计。结果:共发现138例前交通动脉瘤患者;425例被诊断为大脑前动脉A1段发育不良,其中60例伴发前交通动脉瘤。在有大脑前动脉A1段发育不良的患者中前交通动脉瘤的发生率高达14.1%,明显高于无大脑前动脉A1段发育不良的患者中的前交通动脉瘤发生率(1.0%)(P<0.001)。结论:3D-TOF-MRA可以清晰地显示大脑前动脉A1段发育不良与前交通动脉瘤的形态细节,大脑前动脉A1段发育不良伴随着较高的前交通动脉瘤形成可能。Purpose： The aim of this study was to detect and assess A1 segment hypoplasia based on a large case series and investigate the potential links with AcomA aneurysm occurrence using magnetic resonance angiography （MRA）. Methods： Between January 2009 and December 2012, 8013 patients underwent 3D-TOF-MRA examination. MRA was performed using a three-dimensional time-of-flight technique （3D-TOF） with volume rendering （VR） reconstruction. The presence and location of A1 segment hypoplasia and AcomA aneurysm was reviewed based on VR images and source images. Results： Among the 8013 patients examined and reviewed, 138 patients were identified with AcomA aneurysms, 425 patients were defined with A1 segment hypoplasia, among whom 303 were with right-sided A1 hypoplasia and 122 with left-sided A1 hypoplasia. Sixty of these 425 patients were confirmed with AcomA aneurysms, among them 49 were with right-sided A1 hypoplasia and 11 with left-sided A1 hypoplasia. The prevalence ofAcomA aneurysm with A1 segment hypoplasia was 14.1%, which was much higher than that （1.0%） of AcomA aneurysm without A1 segment hypoplasia （P〈0.001）. Conclusion： The anatomical relationship between A1 segment hypoplasia and AcomA aneurysms was visualized by MRA, which displayed anomalies with sufficient clarity to enable diagnosis. The incidence of right-sided A1 segment hypoplasia accompanied with AcomA aneurysm was much higher than that of left-sided. Intracranial AcomA aneurysm development appeared to be associated with A1 segment hypoplasia.

关 键 词：磁共振血管成像 A1段发育不良 前交通动脉瘤 发生率 

分 类 号：R743[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]