双通道视觉质量分析系统对高度近视性黄斑劈裂患者视觉质量的客观定量测量  

Objective quantitative assessment of visual quality with a double-pass instrument for myopic foveoschisis patients

作　　者：李轻宸 高鹏[1] 李欢欢[1] 雒旭[1] 高新蕊[1] 王方[1] 汪浩[1] 

机构地区：[1]上海市第十人民医院眼科,200072

出　　处：《中华眼底病杂志》2016年第1期47-51,共5页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的客观定量评估高度近视黄斑劈裂（MF）患者的视觉质量。方法横断面研究。临床检查确诊的高度近视黄斑劈裂（MF）患者19例19只眼（近视劈裂组）、无黄斑劈裂高度近视21例21只眼（近视对照组）及无高度近视正常者22名22只眼（正常对照组）纳入研究。所有受检者均行医学验光、最佳矫正视力（BCVA）检查以及眼轴长度（AL）测量。采用双通道视觉质量分析系统（0QASⅡ）测量受检眼调制传递函数截止频率（MTFout—off）、斯特列尔比（SR）、客观散射指数（OSI）。采用Pearson分析最小分辨角对数（10gMAR）BCVA、AI。与MTFcut—off、SR、OSI之间的相关性。结果近视劈裂组、近视对照组、正常对照组受检眼平均MTFcut—off、SR、OSI值比较，差异均有统计学意义（F=76．00、116．15、165．77，P〈0．05）。两两比较，近视劈裂组与近视对照组受检眼SR平均值差异无统计学意义（P〉0．05）；其余任意两组间MTFcut—off、SR、OSI值差异有统计学意义（P〈0．05）。近视劈裂组患眼logMARBCVA、AL分别与MTF cut—off（r=-0．928、-0．658，P〈0．05）、SR呈负相关（r=-0．577、-0．893，P〈0．05）；近视对照组患眼logMARBCVA与MTFcut—off、SR呈负相关（r=-0．659、-0．806，P〈0．05）；正常对照组受检眼logMARBCVA与MTFcutoff、SR呈负相关（r=-0．606、-0．602，P〈0．05），与OSI呈正相关（r=0．561，P〈0．05）。结论MF患者BcVA、MTFcut—off、SR、OSI值均低于无劈裂近视患者及正常人群；BcVA、AI。与MTFcut—off、SR值之间呈负相关；BcvA、MTFcut—off、SR值在正常人群、无劈裂高度近视人群和MF患者中依次降低，OSI值逐渐增加。Objective To objectively quantitative assess the visual quality in patients with myopic foveoschisis （MF） using a double-pass optical quality analysis system （QASⅡ）. Methods Sixty-two subjects participated in this cross sectional, observational study, who were divided into three groups based on the pathologic conditions including myopic foveoschisis group （MFG）, myopic control group （MCG） and normal control group （NCG）. Measurements with OQAS II were performed for the modulation transfer function cut off frequency （MTF cut-off）, the Strehl ratio （SR） and the objective scatter index （OSI）. Visual data were analyzed using ANOVA and Pearson＇s correlation accompanied by logMAR BCVA and axial length （AL）. Results The mean values for MTF cut-off, SR and OSI of MFG, MCG and NCG were 18. 18±4.81, 0. 13＋ 0.03, 3.50±0.44; 22.87±2.66, 0.14±0.02, 2.42±0.29; 33.68±4.70, 0.23±0.02, 1.68±0.20 respectively, and statistical difference were proved except SR between MFG and MCG, or BCVA between MCG and NCG （P 〈 0.05）. LogMAR BCVA and AL have negative correlations to MTF cut-off （r = - 0. 928, -0. 658; P〈0.05） and SR （r= -0. 577, -0. 893; P〈0. 05） with high coefficients in MFG. Log MAR BCVA has negative correlations to MTF cut-off and SR （r=-0. 659, -0. 806; P〈0.05） in MCG. Log MAR BCVA has negative correlations to MTF cut off and SR （r = - 0. 606, -0. 602; P〈 0.05） and positively correlated to OSI （r=0. 561, P〈0.05） in NCG. Conclusions The mean value of BCVA, MTF cut-off, SR, OSI of myopic foveoschisis patients were lower than those myopic patients without foveoschisis and normal people, there exists a significant negative correlation between Log MAR BCVA, AL to MTF cut-off and SR. Compared with myopic and normal subjects, myopic foveoschisis have lower BCVA, MTF cut-off, SR but higher OSI.

关 键 词：视觉 眼 视力试验 视网膜劈裂症 近视 退行性/并发症 

分 类 号：R778.11[医药卫生—眼科] R774.1[医药卫生—临床医学]