前列腺癌和良性前列腺增生患者红细胞分布宽度的差异  

Difference of red blood cell distribution width between patients with prostate cancer and benign prostatic hyperplasia

作　　者：胡秦[1] 李纲[1] 张学锋[1] 殷虎明 王力[1] 陈晔[1] 浦金贤[1] 侯建全[1] 

机构地区：[1]苏州大学附属第一医院泌尿外科,江苏省215006

出　　处：《江苏医药》2016年第1期29-31,共3页Jiangsu Medical Journal

基　　金：江苏省医学重点人才基金(RC2011108)

摘　　要：目的探讨前列腺癌(PCa)和良性前列腺增生(BPH)患者红细胞分布宽度(RDW)的差异。方法回顾性分析877例经直肠前列腺穿刺活检患者的RDW值,比较PCa组(385例)和BPH组(492例)患者RDW值的差异。绘制ROC曲线确定RDW诊断PCa的最佳界值,比较不同RDW值的穿刺阳性率。结果 PCa组患者RDW值为(13.34±1.24)%,高于BPH组的(12.78±0.64)%(P<0.01)。取13.05%作为诊断PCa的界值,RDW值>13.05%和≤13.05%穿刺患者的前列腺穿刺阳性率分别为59.3%和32.6%(P<0.01)。结论 RDW可能是PCa的一种预测因素,RDW值>13.05%时前列腺穿刺活检的阳性率增加。Objective To investigate the difference of red blood cell distribution width （RDW） between the patients with prostate cancer （PCa） and benign prostatic hyperplasia （BPH）. Methods RDW values of 877 consecutive patients underwent prostate biopsy were retrospectively analyzed. The difference of RDW values was compared between PCa cases（group PCa, 385 cases） and BPH cases （group BPH,492 cases）. The optimal cutoff value of RDW for the diagnosis of PCa was determined with the ROC curve. The positive rate of prostate biopsy was compared between two groups. Results RDW was higher in group PCa than that in group BPH[（13.34± 1.24）% vs. （12.78±0. 64）%] （P〈0. 01）. Taking 13.05% as the cutoff value in predicting the positive prostate biopsy, the positive prostate biopsy rate was 59.3% in the cases with RDW ≤13.05% and 32.6% in those with RDW ≤13.05%（P〈0. 01）. Conclusion RDW may be a predicting factor for PCa. The positive rate of prostate biopsy increases in the patients with RDW greater than 13.05%.

关 键 词：红细胞分布宽度 前列癌 良性前列腺增生 

分 类 号：R737[医药卫生—肿瘤]