Gd-EOB-DTPA增强MRI对肝细胞癌的诊断价值  

The value of Gd-EOB-DTPA-enhanced MRI in the detection of HCC

作　　者：刘曦娇[1] 唐鹤菡[1] 林丽丽[1] 刘洋洋[1] 陈国勇[1] 蔡磊[1] 黄子星[1] 宋彬[1] 

机构地区：[1]四川大学华西医院放射科,成都610041

出　　处：《放射学实践》2016年第1期26-29,共4页Radiologic Practice

基　　金：国家自然科学基金面上项目资助项目(81171338;81471658)

摘　　要：目的:探究Gd-EOB-DTPA增强MRI对肝细胞瘤(HCC)的诊断价值。方法:纳入因疑诊HCC行Gd-EOBDTPA增强MRI检查的患者48例。将患者图像分成A、B两组,A组包括平扫图像和动态增强图像;B组包括平扫图像、动态增强图像及肝胆期图像。比较两位阅片者在两组图像下诊断HCC的敏感度、特异度、阳性预测值和阴性预测值,并进行统计学分析。结果:B组图像诊断所有HCC的敏感度及阴性预测值高于A组图像,差异有统计学意义(P<0.05)。B组图像诊断直径>2.0cm HCC的阴性预测值高于A组图像,差异有统计学意义(P<0.05)。两位阅片者诊断一致性好(Kappa值均>0.70)。结论:含肝胆期的Gd-EOB-DTPA增强MRI能提高HCC的诊断准确度。Objective：To assess the value of Gd-EOB-DTPA-enhanced MRI in diagnosing hepatocellular carcinoma （HCC）. Methods：Forty-eight patients who were suspected of HCC underwent Gd-EOB-DTPA-enhanced MR examinations. The images were devided into two groups and interpreted independently. Group A included plain scan images and dynamic enhanced images,group B included plain scan images, dynamic enhanced images and hepatobiliary phase （HBP） images. The images of the two groups were interpreted by two readers independently. The sensitivity, specificity, positive predictive value and negative predictive value of the two readers in group A and B were compared seperately and blindly. Results：The sensi- tivity and negative predictive value of HCC in group B were statistically higher than those in group A （P〈0.05）. For diam- eter of the lesion on CT image larger than 2cm, the negative predictive value of group B was statistically higher than that of group A （P〈0.05）. Two readers had a good diagnostic accordance （Kappa value〉0.70）. Conclusion： Gd-EOB-DTPA-en- hanced MRI with hepatobiliary phase images can improve the diagnostic accuracy of HCC.

关 键 词：肝细胞癌 Gd—EOB-DTPA 磁共振成像 

分 类 号：R735.7[医药卫生—肿瘤] R445.2[医药卫生—临床医学]