直肠神经内分泌肿瘤的诊断与治疗(附14例报告)  

Diagnosis and treatment of rectal neuroendocrine tumor: a report of 14 cases

作　　者：陈利文[1] 

机构地区：[1]上海市第八人民医院胃肠外科,上海200235

出　　处：《外科理论与实践》2015年第6期515-517,共3页Journal of Surgery Concepts & Practice

摘　　要：目的:分析直肠神经内分泌肿瘤(neuroendocrine tumor,NET)的临床诊断及治疗。方法 :对14例直肠NET临床及病理资料进行回顾分析并随访。结果:瘤体直径<1 cm 8例,≥1 cm且<2 cm 4例,2 cm 1例,3 cm 1例。瘤体直径<2 cm的12例,实施经肛门局部切除术3例,内镜下黏膜切除术9例。瘤体直径≥2 cm的2例,行低位直肠前切除术。13例获访者无死亡病例。结论:直肠NET生物学行为低度恶性,瘤体直径<2 cm的一般不侵犯肌层,也很少转移,大多数病例可经肛门局部切除或行内镜黏膜切除术治愈。Objective To analyze the diagnosis and treatment in rectal neuroendocrine tumor. Methods The clinical and pathological data of 14 cases with rectal neuroendocrine tumor were analyzed retrospectively. Results Tumor diameter was〈1 cm in 8 cases,≥1 cm and〈2 cm in 4 cases and that in other 2 cases was 2 cm and 3 cm respectively. The treat-ment for 12 cases with tumor〈2 cm of diameter was transanal local resection in 3 cases and endoscopic mucosal resection in 9 cases. Low anterior resection was performed in 2 cases with tumor ≥2 cm of diameter. Thirteen patients were followed and all survived. Conclusions The results of our study showed that the biological behavior of rectal neruoendocrine tumor is low malignant potential. The lesions with〈2 cm of diameter do not invade muscularis propria and rarely metastasize. Most of the patients could be cured by local resection including transanal local excision and endoscopic mucosal resection.

关 键 词：直肠肿瘤 直肠神经内分泌肿瘤 治疗 

分 类 号：R735.37[医药卫生—肿瘤]