气相色谱-串联质谱法测定牛奶中16种邻苯二甲酸酯类化合物  

Determination of 16 phthalate esters in milk by gas chromatography-tandem mass spectrometry

作　　者：党富民[1] 卢春霞[1] 孙凤霞[1] 方婷婷[1] 谢勇[1] 罗小玲[1] 

机构地区：[1]新疆农垦科学院农业部食品质量监督检验测试中心(石河子),新疆石河子832000

出　　处：《化学研究与应用》2016年第1期139-144,共6页Chemical Research and Application

基　　金：国家科技支撑计划项目(2012BAD43B03)资助;国家自然科学基金项目(21567027)资助;新疆生产建设兵团博士基金项目(2014BB007)资助

摘　　要：建立了牛奶中16种邻苯二甲酸酯的气相色谱-串联质谱(GC-MS/MS)检测方法。样品经正己烷提取后进行检测,GC-MS/MS定量分析。16种邻苯二甲酸酯在5~1000μg·L^(-1)浓度范围内呈良好线性,相关系数均大于0.990,检出限在0.001~0.03 mg·kg^(-1)之间。3个浓度梯度(0.10、1.0、10.0 mg·kg^(-1))的平均回收率在83%~116%,相对标准偏差(RSD,n=6)在1.9%~8.9%。方法灵敏度高、定性定量准确、重现性好,专属性强,适用于牛奶中邻苯二甲酸酯的检测。Objective to establish a method for the determination of 16 phthalate esters（ PAEs） in milk by gas chromatography-tandem mass spectrometry（ GC-MS/MS）. The samples were extracted with hexane,and were detected by GC-MS/MS. The substrate spiked standard curves of16 phthalate estershad good linear correlations in the range 5 ~ 1000μg·L^（-1）,with all correlation coefficients above0. 990. The detection limits of 16 PAEs were 0. 001 to 0. 03 mg·kg^（-1）. The average recoveries of there concentrations（ 0. 10、1. 0、10. 0 mg·kg^（-1）） were ranged between 83%and 116%,and the relative standard deviations（ RSD,n = 6） were ranged between 1. 9%and 8. 9%. This method is highly sensitive,accurate,reproducible and proprietary.It is suitable for the detection of PAEs in milk.

关 键 词：气相色谱-串联质谱 邻苯二甲酸酯 塑化剂 牛奶 

分 类 号：O657.7[理学—分析化学]