68例上腔静脉压迫综合征放化疗疗效分析  

The effect of chemoradiotherapy for 68 cases of superior vena cana syndrome

作　　者：陈佳权 崔玉梅 

机构地区：[1]恩施土家族苗族自治州中心医院肿瘤1科,湖北恩施445000 [2]恩施市中心医院泌尿外科,湖北恩施445000

出　　处：《现代肿瘤医学》2016年第3期463-465,共3页Journal of Modern Oncology

摘　　要：目的:分析我院68例上腔静脉压迫综合征患者治疗的近期疗效及1、2、3年生存率。方法:43例患者(小细胞肺癌未分化30例,非霍奇金淋巴瘤10例,非精原细胞瘤2例,畸胎瘤1例)先给予一周期化疗,化疗结束后第3天开始放疗(先化疗组),其余25例患者在放疗结束后给予化疗(先放疗组)。化疗方案:EP、CHOP、BEP、NP、TP、GP、DF。结果:对于恶性肿瘤导致的上腔静脉压迫综合征患者,放化疗是有效的治疗措施,本组资料显示先化疗组较先放疗组1年、2年、3年生存率高。结论:根据病理类型及病情确定首次治疗方式尤为重要。对于小细胞肺癌、淋巴瘤、生殖系统肿瘤宜首选化疗,而对非小细胞肺癌、胸腺瘤、食管癌及其他肿瘤宜首选放疗,尤其在病情危急时宜首选放疗,其症状和体征出现缓解的可能性较高,但这些患者总的预后不良。Objective：To analyze the efficacy and 1,2,3 years survival rate for 68 cases with SVCS （superior vena cana syndrome） in our hospital. Methods ：43 patients（ small cell anaplastie carcinoma of the lung 30, non Hodgking lymphoma 10, nonseminoma 2, teratoma 1 ） were the first chemotherapy group, treated firstly with one cycle of chemotherapy, and then radiotherapy in the third day of chemotherapy. The other 25 patients were the first radiotherapy group, given firstly radiotherapy, then chemotherapy. Results ： Chemoradiotherapy could have better therapeutic effect in SVCS. The first chemotherapy group were better than the first radiotherapy group in 1,2,3 years survival rate. Conclusion：The first treatment is very important according to the pathological type. Chemotherapy is the primary treatment for SCLC（small cell lung cancer） ,ML（malignant lymphoma） and genitourinary tumors,but radiotherapy for non -small cell lung cancer, thymoma, esophagus cancer.

关 键 词：上腔静脉压迫综合症 放疗 肺癌 非霍奇金淋巴瘤 胸腺瘤 

分 类 号：R730.58[医药卫生—肿瘤]