全肠内营养在急性重症胰腺炎胰腺坏死性感染的作用分析  

作　　者：刘海峰[1] 赵浩亮[1] 田彦璋[1] 

机构地区：[1]山西医科大学附属山西医学科学院山西大医院,山西030001

出　　处：《当代医学》2016年第3期86-87,共2页Contemporary Medicine

摘　　要：目的评价全肠内营养在重症胰腺炎胰腺坏死性感染中的作用。方法选择60例确诊为重症胰腺炎入住ICU的患者作为观察对象,采用随机数表法将患者分为2组,各30例。观察组采用全肠内营养联合抗生素治疗,对照组采用全肠外营养联合抗生素治疗,观察2组患者外科干预情况及胰腺感染坏死类型、病死率等情况。结果观察组手术干预、再手术患者比例(36.67%)及手术出血量(80±10)m L低于对照组,差异有统计学意义(P<0.05);观察组从发病到手术时间(25.9±2.1)d较对照组长,差异有统计学意义(P<0.05);2组在手术持续时间方面差异无统计学意义;观察组主要以无菌性坏死为主,对照组以感染性坏死为主,差异有统计学意义(P<0.05);观察组病死率为13.33%,对照组为36.67%,差异有统计学意义(P<0.05);观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论重症急性胰腺炎坏死性感染患者应优先进行全肠内营养,效果较好。Objective To evaluate the prevention effect of total internal nutrition in pancreatic necrotic infection of severe acute pancreatitis. Methods 60 cases with severe acute pancreatitis were enrolled. The patients were divided into two groups named observation group and control group, and each group contains 30 patients. The observation group received total internal nutrition and the control group received total parenteral nutrition, the incidence rate of pancreatic septic necroses, surgical intervention as well. as complication rate were observed. Results Proportion of surgical intervention （36.67%） and blood loss （80-10）mL in observation group were lower than control group （P〈0.05）. The operative time in the observe group （25.9-2.1）d was longer than control group （P〈0.05）. Aseptic necrosis was observed mainly in the observation group, while infection necrosis was mainly in control group （P〈0.05）. The incidence rate in observation group was 13.33 percent and 36.67 percent in control group （P〈0.05）. The complication rate in observation group was lower than in the control group （P〈0.05）. Conclusion Total internal nutrition is prior than total parenteral nutrition in prevention of pancreatic necrotic infection in severe acute pancreatitis.

关 键 词：重症胰腺炎 全肠内营养 感染 手术治疗 

分 类 号：R576[医药卫生—消化系统]