T_2期胃癌临床病理特征及多层螺旋CT术前TNM分期价值  

The clinicopathology features of the T_2 gastric cancer and value of enhanced multiphasic spiral CT in TNM staging of T_2 gastric cancer

作　　者：郭辰[1] 任刚[1] 蔡嵘[2] 戚庭月[3] 赵建溪 陈健[1] 李华莉[1] 贺文广[1] 李文华[1] 汪登斌[1] 吴湘如[4] 张文杰[5] 

机构地区：[1]上海交通大学医学院附属新华医院放射科,上海200092 [2]上海交通大学医学院附属瑞金医院放疗科,上海200025 [3]江苏省扬州市第一人民医院超声科,225001 [4]上海交通大学医学院附属新华医院病理科,上海200092 [5]上海交通大学医学院附属新华医院普外科,上海200092

出　　处：《重庆医学》2016年第3期362-365,共4页Chongqing medicine

基　　金：江苏省科技计划基金资助项目(BL2014064);上海交通大学医学院科研基金资助项目(09XJ21013);上海市卫生局科研基金资助项目(2010029);上海市卫生局科研基金资助项目(2010057);上海市科委科研基金资助项目(124119a0300);上海市教委科研基金资助项目(12Y2034)

摘　　要：目的探讨T_2期胃癌临床病理特征及多层螺旋CT(MSCT)在T_2期胃癌术前TNM分期中的价值。方法单因素分析93例T_2期胃癌患者的临床病理特征,并行MSCT术前TNM分期,与术后病理检查结果进行对照。结果浅肌层癌(T_2a)和深肌层癌(T_2b)两组患者在临床病理特征上差异无统计学意义(P>0.05)。MSCT对T_2期胃癌T分期准确率为91.40%(85/93);N分期准确率为66.67%(62/93),其中对pN0、pN1、pN2和pN3期判断的准确率分别为68.18%(30/44)、65.00%(26/40)、60.00%(3/5)和75.00%(3/4);TNM分期的准确率为67.74%(63/93),其中Ⅰ、Ⅱ、Ⅲ和Ⅳ期分期准确率分别为68.18%(30/44)、64.10%(25/39)、60.00%(3/5)和100%(5/5)。结论 T_2a和T_2b患者在临床病理特征上没有显著差异。MSCT动态增强扫描对T_2期胃癌术前TNM分期具有重要的临床价值。Objective To explore the clinicopathological characters of T2 gastric cancer and the value of MSCT in the preop- erative TNM staging of T2 gastric cancer. Methods A total of 93 patients with T2 gastric cancer were included in our study and un- derwent preoperative MSCT staging, who were confirmed by pathologic results. Then the results were compared with those of path- ologic TNM staging. Also the clinicopathological features of the T2 gastric cancer were analyzed. Results There were no statistical- ly significant differences in the clinicopathological characters among Tza and T26 patients （P〉0.05）. Comparing with pathologic TNM stage, the T staging accuracy of MSCT was 91.40 % （ 85 / 93 ）, the N staging accuracies of CT was 66.67 0% （62 / 93）, in which, 68.18%（30/44）,65.00%（26/40）,60.00%（3/5） and 75. 00%（3/4） were for pN0,pN1,pN2 and pN3. And the TNM staging ac- curacies of CT was 67.74% （63/93） ,in which,68.18% （30/44）,64.10%（25/39）,60.00% （3/5） and 100% （5/5） were for stage Ⅰ , Ⅱ ,Ⅲand Ⅳ. Conclusion There are no significant different on clinicopathology features among T2a and T2b patients. MSCT can clearly determine the preoperative TNM staging of T2 gastric cancer.

关 键 词：体层摄影术 螺旋计算机 胃肿瘤 肿瘤分期 T2期胃癌 多层螺旋CT 术前TNM分期 临床病理特征 

分 类 号：R735.2[医药卫生—肿瘤] R730.44[医药卫生—临床医学]