羟基磷灰石-聚乳酸复合膜的制备与表征  

Preparation and characterization of hydroxyapatite-polylactic acid HA-PLA composite film

作　　者：袁秋华[1] 巫剑波 秦草坪 郭志威[1] 刘家裕[1] 林松鑫 柯善明[2] 张培新[1] 

机构地区：[1]深圳大学化学与环境工程学院,广东深圳518060 [2]深圳大学材料学院,广东深圳518060

出　　处：《深圳大学学报（理工版）》2016年第1期10-17,共8页Journal of Shenzhen University(Science and Engineering)

基　　金：国家自然科学基金资助项目(21471102;20971088);深圳市科技基础研究计划资助项目(JCYJ20150525092941007)~~

摘　　要：采用化学沉淀法制备羟基磷灰石粉体,通过溶液共混、磁力搅拌的方法制备羟基磷灰石-聚乳酸(hydroxyapatite-polylactic acid,HA-PLA)悬浮液,在不锈钢304基体表面采用旋涂法涂覆HA-PLA复合膜.研究在300℃(空气)、600℃(空气)、300℃(氮气)和800℃(氮气)等不同热处理条件对HA-PLA复合膜组成和形貌的影响.所制备的复合膜通过X射线衍射、傅里叶变换红外光谱、扫描电子显微镜、X射线能量色散仪、热重-差热分析和X射线光电子能谱等测试手段进行表征.结果表明,所制备的HA-PLA复合膜结晶度好、纯度较高、不存在杂质相;600℃(空气)热处理后的HA-PLA复合膜能达到黏结致密、无裂缝效果,且无需置于无氧及800℃高温条件下处理,在600℃温度条件下PLA分解残留的碳残片可有效阻止HA分解成其他杂质.Hydroxyapatite powders were synthesized by chemical precipitation method. Hydroxyapatite-polylactic acid（ HA-PLA） composite films were coated on 304-type stainless steel substrates by HA-PLA suspension,which was prepared via solution blending and magnetic stirring,with spin coating technique. The effects of heat treatment under air atmosphere at 300 ℃,600 ℃ and nitrogen atmosphere at 300 ℃,800 ℃ on the composition and morphology of HA-PLA composite films were studied. The composite films were characterized by means of X-ray diffraction（ XRD）,Fourier transform infrared spectroscopy（ FTIR）,scanning electron microscopy（ SEM） coupled with energy-dispersive X-ray spectroscopy（ EDX）,thermogravimetric analysis-differential thermal analysis（ TG-DTA）,and X-ray photoelectron spectroscopy（ XPS）. The results show the prepared HA-PLA composite films exhibit highcrystallinity and purity,and through the heat treatment under air atmosphere at 600 ℃ instead of nitrogen atmosphere at 800 ℃,dense adhesion and crack-free composite coatings can be finally achieved. Under this condition（ heat treatment at 600 ℃）,PLA is decomposed into char residues which function as inhibiting further decomposition of HA into other impurities.

关 键 词：生物材料学 羟基磷灰石 聚乳酸 旋涂法 复合膜 热处理 

分 类 号：TQ174.759[化学工程—陶瓷工业]