不同遗传背景儿童在不同调节状态下眼前节结构的变化  

Changes in the anterior segment of eyes of children with different genetic background under different accommodations

作　　者：戴怡康[1] 傅伟才[1] 陆玮瑜[1] 柳林[1] 

机构地区：[1]上海交通大学医学院附属仁济医院眼科,上海200127

出　　处：《上海交通大学学报（医学版）》2016年第1期80-82,88,共4页Journal of Shanghai Jiao tong University:Medical Science

基　　金：上海市自然科学基金(11ZR1421300)~~

摘　　要：目的研究和分析不同遗传背景下,相同屈光状态儿童在不同的调节刺激下眼前节结构的变化。方法采集正视眼儿童(+0.50^-0.50 DS)60例(60眼),分成2组:A组30例,儿童父母均为正视;B组30例,父母均为高度近视(≥6.0 DS)。所有受试儿童行散瞳主觉验光,调节放松和不同程度调节刺激下测量前房深度、晶状体厚度及暗瞳直径,比较两组间的差异。结果两组儿童的年龄、调节幅度和裸眼视力差异均无统计学意义(P>0.05)。调节放松和诱发3D调节时两组间各测量指标的差异无统计学意义(P>0.05)。诱发6D调节时,A组前房深度变浅值和晶状体变厚值均大于B组(P<0.05),但暗瞳直径缩小值两组之间的差异无统计学意义(P>0.05)。结论在6D调节刺激下,父母均为高度近视的儿童眼前节结构中前房深度以及晶状体厚度变化值均小于父母均为正视的儿童,这种差异是否造成今后屈光转归的不同尚需进一步研究。Objective To investigate and analyze the changes in the anterior segment of eyes of children with different genetic background and same refraction under different accommodations. Methods A total of 60 emmetropic children （60 eyes, ＋0.50 - -0.50 DS） were enrolled and divided into A group （n =30） and B group （ n =30）. Parents of children of A group were emmetropic and parents of children of B group were highly myopic （≥ 6.0 DS）. All children underwent subjective refraction after mydriasis. The anterior chamber depth, crystalline lens thickness, and dark pupil diameter were measured under relaxation and different accommodations. The difference between two groups was compared. Results The differences of age, accommodation amplitude, and naked vision between two groups were not statistically significant （P 〉0.05）. The differences of measurements under relaxation and accommodation of 3D between two groups were not statistically significant （P〉0.05）. The decrease of anterior chamber depth and the increase of crystalline lens thickness of A group under accommodation of 6D were larger than those of B group （P〈0.05）, while the difference of the decrease of dark pupil diameter between two groups was not statistically significant （P 〉0.05） . Conclusion Changes of anterior chamber depth and crystalline lens thickness in the anterior segment of eyes of children with highly myopic parents under accommodation of 6D are smaller than those of children with emmetropic parents. Whether this difference leads to the difference of refraction in the future still needs further study.

关 键 词：遗传 近视 调节 眼前节结构 

分 类 号：R778.11[医药卫生—眼科]