转移性结直肠癌原发肿瘤的外科治疗现状  

Surgical Therapeutic Progression of the Primary Tumor in Metastatic Colorectal Cancer Patients

作　　者：王福刚[1,2] 张明星[1,2] 宋希林[2] 

机构地区：[1]山东省医学科学院济南大学医学与生命科学学院,临床医学在读研究生济南250117 [2]山东省肿瘤医院胃肠外科,济南250117

出　　处：《医学综述》2016年第2期255-258,共4页Medical Recapitulate

摘　　要：目前对于转移性结直肠癌(MCRC)患者是否行原发肿瘤切除(PTR)仍然存在争议。MCRC患者行PTR能使患者获得更长的中位生存期(MS),但PTR的适应证、PTR时机、手术并发症与病死率目前仍不明确。该研究通过对以往文献的回顾,证实新辅助化疗后的MCRC患者行PTR有更好的疗效,同时也证实PTR较非PTR的其他手术方式能够降低手术并发症及手术病死率。临床上年龄<65岁、肝脏转移程度较轻、无广泛转移及肿瘤分化较好的MCRC患者行PTR可获得更好的效果。At present, there is still controversy about whether the primary tumor resection （PTR） should be done for patients with metastatic coloreetal cancer（MCRC）. MCRC patients treated with PTR can make the patients achieve longer in the median survival（MS） , but the indications of PTR, PTR timing, surgical complications and mortality are still not clear. The study confirmed that PTR after neoadjuvant chemotherapy had better effect on MCRC patients, and it also confirmed that PTR could reduce the operative complications and mortality than other non-PTR procedures. The clinical effect of PTR was better for patients with age of 〈 65 years, lighter liver metastasis degree, and patients without wide range of metastasis and differentiation.

关 键 词：结直肠肿瘤 转移 外科治疗 

分 类 号：R735.3[医药卫生—肿瘤]