胃黏膜癌前病变患者行幽门螺杆菌根除治疗的研究进展  

Research Progress of Eradication of Helicobacter Pylori for Patients with Precancerous Lesions in the Gastric Mucosa

作　　者：覃二元 廖江涛[1] 侯俊良[1] 杨达峰[2] 

机构地区：[1]南华大学附属省马王堆医院消化内科 [2]中南大学附属湘雅医院心内科,长沙410008

出　　处：《医学综述》2016年第2期262-266,共5页Medical Recapitulate

摘　　要：胃癌在全球癌症病死率中位居第二位,而幽门螺杆菌(Hp)感染是促进胃癌发生的主要致癌物之一,因此根除Hp感染是预防胃癌发生的优先方法。但对于有效根除Hp能否逆转癌前病变,阻止胃癌的发生仍然存在争议。而使用抗环加氧酶2与改善癌前病变的关系有待进一步研究。从慢性胃炎发展到胃癌的过程中,根除Hp减少胃癌的发生是否存在"不可逆转"的分界点仍然没有明确。Gastric cancer is the second leading cause of cancer related mortality worldwide, ahd helicobacter pylori （Hp） is one of the important causes of gastric cancer, therefore Hp eradication has been shown to be a primary preventive measure for gastric cancer. The issue of whether eradication of Hp infection could actually reverse premalignant lesions and prevent cancer is still controversial. The relationship hetween the use of anti-COX-2 and improvement of the precancerous lesions needs further study. It＇s still unclear that whether there is an irreversible point of chronic gastritis developing into gastric cancer for Hp eradication prevention.

关 键 词：幽门螺杆菌 根除治疗 癌前病变 

分 类 号：R573.9[医药卫生—消化系统]