甲胎蛋白阴性原发性肝癌诊断进展  

The Progress in Diagnosis of AFP Negative Primary Liver Cancer

作　　者：王静 石明伟 张侠[3] 

机构地区：[1]山西医科大学第二临床医学院 [2]安徽省急救中心,合肥230022 [3]北京军区总医院肿瘤内科诊治中心,北京100007

出　　处：《医学综述》2016年第2期269-273,共5页Medical Recapitulate

摘　　要：原发性肝癌是我国较常见的恶性肿瘤之一,目前其临床诊断于血清学标志物和相关影像学技术。甲胎蛋白作为敏感性及特异性较高的肝细胞癌肿瘤标志物,广泛应用于临床的筛检、早期诊断及治疗过程。但是临床中约有1/3的肝癌患者血清甲胎蛋白水平正常,对于这部分患者,分析甲胎蛋白阴性肝癌病理特征,相关新的特异性标志物的探索,影像学技术的合理应用,是需要进一步研究的内容。Primary liver cancer is one of the more common malignancies in China, and the clinical diagnosis currently depends on serological markers and related imaging techniques. Alpha-fetoprotein（AFP） as a hepatic celluler cancer tumor marker of high sensitivity and specificity, is widely used in the clinical screening, early diagnosis and treatment process. However,about one-third of total cases of liver cancer have normal level of AFP,for these patients,analyzing of pathological features, and exploring new specific markers, rational application of imaging techniques are needed.

关 键 词：原发性肝癌 甲胎蛋白 诊断 

分 类 号：R735.7[医药卫生—肿瘤]