2型糖尿病患者腹胀与小肠细菌过度生长的关系  

Relationship between abdominal distension and small intestine bacterial overgrowth in type 2 diabetic patients

作　　者：张莉[1] 朱惠明[1] 王艳梅[2] 江堤[1] 孙贤久[1] 乐有林 

机构地区：[1]东莞东华医院消化内科,广东东莞523000 [2]河南大学护理学院,河南开封475000

出　　处：《山东大学学报（医学版）》2016年第1期45-47,70,共4页Journal of Shandong University:Health Sciences

摘　　要：目的探讨2型糖尿病患者腹胀与小肠细菌过度生长(SIBO)的关系。方法将96例2型糖尿病患者分为血糖正常且无腹胀组、血糖正常并腹胀组、血糖升高无腹胀组、血糖升高并腹胀4组,通过乳果糖氢呼气试验分别检测其SIBO情况及口盲时间,并与健康对照组进行组间比较分析。结果血糖升高并腹胀组患者的SIBO阳性率较其他组患者明显增高,差异有统计学意义。腹胀组SIBO阳性率与健康对照组比较有统计学差异(P<0.05),4组患者口盲时间与健康对照组比较均有统计学意义(P<0.01)。结论 2型糖尿病合并腹胀患者易发生SIBO,与口盲时间延长相关,其可能是腹胀发生的重要发病机制。Objective To explore the relationship between abdominal distension and small intestine bacterial overgrow th（ SIBO） in type 2 diabetic patients. Methods A total of 96 type 2 diabetic patients were divided into 4 groups： normal blood glucose and no abdominal distention group（ control group）,normal blood glucose and abdominal distension group（ abdominal distension group）,hyperglycemia without abdominal distension group,and hyperglycemia and abdominal distention group. SIBO and the mouth-intestine transit time were detected with lactulose hydrogen breath test,and the results of the control group were compared with those of the other groups. Results The positive rate of SIBO in the hyperglycemia and abdominal distention group was higher than in the other groups,and the difference was significant. There was difference in the positive rate of SIBO between the control group and abdominal distension group（ P 〈0. 05）. There were significant differences in the mouth-intestine transit time between the control group and the other 3groups（ P〈 0. 01）. Conclusion Type 2 diabetic patients with abdominal distention are more liable to have SIBO. The long mouth-intestine transit time may be related to abdominal distension.

关 键 词：2型糖尿病 小肠细菌过度生长 氢呼气试验 

分 类 号：R575[医药卫生—消化系统]