窄带成像技术与碘染色诊断早期食管癌及其癌前病变的对比研究  被引量:25

A comparative study between narrow-band imaging (NBI) and iodine chromoscopy for early esophageal cancer and precancerous lesions

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作  者:张惠晶[1] 周环[1] 矫太伟[1] 冯明亮[1] 刘梦园[1] 孙明军[1] 

机构地区:[1]中国医科大学附属第一医院内镜诊治科,沈阳110001

出  处:《中华消化内镜杂志》2016年第1期33-36,共4页Chinese Journal of Digestive Endoscopy

摘  要:目的评价窄带成像技术(NBI)对早期食管癌及其癌前病变的诊断价值。方法2013年1月至2014年7月,170例(192处病变)病理检查确诊为早期食管癌及其癌前病变患者纳入回顾性分析,对比分析其普通内镜、NBI内镜及碘染色内镜的检出情况。结果早期食管癌检出率NBI为100.0%(13/13),碘染色亦为100。0%(13/13),两者差异无统计学意义(P〉0.05)。高级别上皮内瘤变NBI及碘染色的检出率分别为94.9%(94/99)和100.0%(99/99),两者间差异无统计学意义(P〉0.05);低级别上皮内瘤变NBI及碘染色的检出率分别为78.8%(63/80)和100.0%(80/80),碘染色明显高于NBI(P〈0.01)。结论NBI及碘染色内镜对早期食管癌均有较好的诊断价值,对于癌前病变中的高级别上皮内瘤变两者诊断价值相近,但对于低级别上皮内瘤变NBI诊断价值不及碘染色。Objective To evaluate narrow-band imaging(NBI)for early esophageal cancer and precancerous lesions. Methods A total of 170 patients (192 lesions ) diagnosed as having superficial esophageal carcinoma and precancerous lesions by endoscopy were retrospectively analyzed. Clinical data of endoscopy, narrow-band imaging (NBI) and iodine chromoscopy were analyzed.Results The detection rates of early esophageal cancer were both 100. 0% in NBI(13/13) and iodine staining ( 13/13), with no statistically significant difference (P〉0.05).The detection rate of high grade intraepithelial neoplasia in NBI and iodine staining was 94. 9% (94/99) and 100.0% (99/99) respectively with no statistically significant difference (P〉0. 05) ; The detection rate of low grade intraepithelial neoplasia in iodine staining was 100. 0% (80/80), significantly higher than that of NBI 78.8% (63/80) (P〈0. 01 ). Conclusion NBI and iodine staining endoscopy show better diagnostic value for early esophageal cancer and similar diagnostic value for high grade intraepithelial neoplasia in precancerous lesions. But for the low grade intraepithelial neoplasia, the diagnostic value of iodine staining endoscopy is better than that of NBI.

关 键 词:食管肿瘤 癌前病变 染色与标记 内窥镜检查 窄带成像技术 

分 类 号:R735.1[医药卫生—肿瘤]

 

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