西藏高原地区超选择子宫动脉灌注化疗及栓塞术治疗恶性滋养细胞肿瘤的临床价值  

Clinical value of Tibet plateau area super selective arterial embolization in the treatment of malignant trophoblastic tumor hemorrhage

作　　者：雷彦明[1] 方印[1] 周小红[2] 

机构地区：[1]西藏自治区人民医院影像科 [2]西藏自治区人民医院妇产科,西藏拉萨850000

出　　处：《西藏医药》2016年第1期5-7,共3页Tibetan Medicine

摘　　要：目的:探讨超选择性子宫动脉化疗栓塞术在控制恶性滋养细胞肿瘤治疗疗效价值。方法:11例恶性滋养细胞肿瘤病例,经股动脉穿刺超选择性子宫动脉导管插入术和血管造影技术,所有患者通过子宫动脉灌注化疗后栓塞治疗。结果:11例恶性滋养细胞肿瘤患者通过双侧子宫动脉超选择插管局部化疗和栓塞治疗成功,灌注化疗后,行栓塞治疗阴道流血量明显减少,成功控制出血,栓塞术后病人仅表现轻微的疼痛和不同程度的发热,无1例出现严重的并发症,9例(81.8%)患者化学治疗后痊愈,其中4例患者再次妊娠成功并足月分娩。结论:在西藏高原地区通过超选择双侧子宫动脉灌注化疗加栓塞术成为治疗恶性滋养细胞肿瘤的另一种有效方法,此技术具有创伤小、并发症发生率低,可重复性操作等特点,容易被患者接受,疗效佳,因此此项技术值得在西藏高原地区应用,也具有很高的临床价值.Objective： To explore the application value of super selective arterial embolization to control malignant trophoblastic tumor hemorrhage endovascular embohzation. Methods： 11 cases of malignant trophoblastic tumor hemorrhage cases, percutaneous femoral artery puncture line of super selective uterine arterial catheterization and angiography using Seldinger technique, uterine artery embolization after angiography, arterial embolization treatment all patients received chemotherapy. Results： super selective bilateral uterine artery catheterization and embolization was successful in 11 of all patients within 30 min after embolization of bleeding, the amount of vaginal bleeding was significantly reduced, the successful control of hemorrhage, embolism patients showed only a slight pain and varying degrees of fever, 11o serious complications occurred in 1 patients, 9 cases （81.8%） were cured after chemical therapy among them, 4 patients had successful preguancies and term delivery. Conclusion： super selective arterial embolization can effectively control the malignant trophoblastic tumor hemorrhage, is a safe, effective treatment, and retaining the integrity and reproductive function.

关 键 词：滋养层肿瘤 出血 介入性 栓塞 

分 类 号：R737.33[医药卫生—肿瘤]