广西围产儿先天性脑积水的影响因素研究  

Impact factors of perinatal congenital hydrocephalus in Guangxi

作　　者：韦朋海 丘小霞[1] 姚慧[1] 韦萍[1] 刘湘红[1] 曾萼[1] 雷利志[1] 何仲彪[1] 邓泽彬 

机构地区：[1]广西壮族自治区妇幼保健院保健部,南宁市530003

出　　处：《广西医学》2015年第12期1727-1731,共5页Guangxi Medical Journal

基　　金：广西科学研究与技术开发计划(桂科攻1140003B-80;桂科攻1140003B-81;桂科攻1298003-4-2);广西医疗卫生重点科研课题(重2011060);广西医药卫生科研课题(Z2013259)

摘　　要：目的探讨影响广西围产儿先天性脑积水发生的影响因素,为制定相应的防控措施提供参考依据。方法对广西7个市的229例先天性脑积水围产儿的父母和229例正常围产儿的父母进行问卷调查,对可能影响围产儿先天性脑积水发生的因素进行单因素及多因素分析。结果多因素logistic回归分析结果显示,父亲年龄、母亲孕早期患病、母亲孕前或孕期有过物理或化学伤害、在母亲怀孕前半年或孕早期进行房屋装修是广西围产儿先天性脑积水的危险因素,而父亲的教育程度、母亲孕早期接受过优生检测、母亲服用叶酸是保护因素(P<0.05)。结论加强保护因素,减少和控制孕妇孕期的危险因素是预防围产儿先天性脑积水的重要手段。Objective To investigate the impact factors of perinatal congenital hydrocephalus in Guangxi ,and to provide the references for relevant prevention and control measures. Methods A questionnaire survey was performed in 229 parents of perinatal infants with congenital hydrocephalus and 229 patients of normal perinatal infants from 7 cities of Guangxi. Univariate and multivariate analysis were used to analyze the related impact factors of perinatal congenital hydrocephalus. Results Multivariate logistic regression analysis showed that father＇s age,mother＇s suffering from an illness in the first trimester, mother＇s suffering from physical or chemical injuries before or during pregnancy and room decoration during 6 months before pregnancy or in the first trimester were the risk factors for perinatal congenital hydrocephalus in Guangxi, and father＇s education backgroud, mother＇s receiving eugenics detection in the first trimester and mother＇s taking folic acid were the protective factors （ P 〈 0.05 ）. Conclusion Strengthening protective factors as well as reducing and controlling the risk factors of pregnant women during pregnancy period is an important method for preventing the perinatal congenital hydrocephalus.

关 键 词：先天性脑积水 围产儿 危险因素 保护因素 广西 

分 类 号：R742.7[医药卫生—神经病学与精神病学]