代谢组学技术在动物营养代谢病中的应用  

Application of metabonomics in animal nutrition metabolic diseases

作　　者：曹宇[1] 孙玲伟 包凯[3] 王艳辉[1] 夏成[1] 张洪友[1] 

机构地区：[1]黑龙江八一农垦大学,黑龙江大庆163319 [2]江苏省肉羊产业工程技术研究中心,江苏南京210095 [3]上海奶牛育种中心有限公司,上海200436

出　　处：《现代畜牧兽医》2016年第1期52-57,共6页Modern Journal of Animal Husbandry and Veterinary Medicine

基　　金：国家自然科学基金(31072181);国家科技支撑计划课题(2012BAD12B03-2)

摘　　要：随着畜牧业的快速发展,我国对经济动物及其产品的需求日渐增加,高效畜禽品种的选育,动物营养代谢病的发病率日趋增加。作为系统生物学的重要组成部分,代谢组学可对机体代谢物的变化进行定量和定性的检测,为探索各种营养代谢病的发病过程及发病机理提供有力的技术平台。目前代谢组学在人类营养代谢病研究中已取得一定的成果,但在动物的营养代谢病上尚处于起步阶段。本文就代谢组学在动物营养代谢病中的应用进行综述,为今后的研究奠定理论依据。With the rapid development of the stock farming, increased demand for animals prod-ucts, increasingly incidence of variable nutritional metabolic disease. As a part of system biolo-gy, organism metabolites can be quantitative and qualitative detected by metabolites for explor-ing the process and the pathogenesis of various metabolic diseases. Metabolomics had made certain achievements in the study of human disease, but still in its infancy in animal metabolic diseases. In this paper, the application of metabolomics in animal nutrition metabolic disease was reviewed, lay theoretical basis for the future research.

关 键 词：动物营养代谢病 系统生物学 代谢组学 发病机理 

分 类 号：S856[农业科学—临床兽医学]