30例肺部曲霉菌感染的微生物检验与临床诊治体会  

Clinical diagnosis and microbiological examination of 30 patients with pulmonary aspergillus infection

作　　者：全博[1] 黄晓英[2] 胡章良[3] 

机构地区：[1]湖北省荆州市第二人民医院检验科微生物室,434000 [2]湖北省荆州市第二人民医院控感办,434000 [3]湖北省荆州市第二人民医院呼吸科,434000

出　　处：《检验医学与临床》2015年第A02期73-74,共2页Laboratory Medicine and Clinic

摘　　要：目的：探讨本院30例肺曲霉菌感染患者的微生物诊断流程，分析与临床诊断一致性。方法对本院2010年1月至2015年3月入院治疗的30例痰培养或肺支气管灌洗液多次培养为曲霉菌，经临床结合影像学特点和其他临床指征，参照侵袭性肺部真菌（IFD）感染的诊断标准和治疗原则（草案）[1]和美国胸科协会（ATS）[2]的相关指南，确诊的或用抗真菌治疗有效的30例性肺曲霉菌感染患者进行回顾性分析，总结微生物诊断流程和与临床的诊断一致性。结果结论本组病例曲霉菌微生物结果与临床诊断结果一致。肺曲霉菌感染发展迅速，而且病死率相对较高，早期没有明确临床指征和诊断依据时，痰培养和痰涂片曲霉菌阳性结果可对诊断提示方向，准确及时的诊断能够促进临床治疗的成功率，提高患者的满意度，推进临床对肺曲霉病诊疗水平。Objective To evaluate the microbiological diagnosis of 30 patients with pulmonary aspergillus in‐fection in our process ,analysis and clinical diagnosis of consistency .Methods In our hospital between January 2010 and March 2010 hospital treatment of 30 cases of sputum cultivation or pulmonary bronchial lavage times for asper‐gillus ,the clinical imaging characteristics and other clinical indications ,reference to invasive pulmonary fungus infec‐tion （IFD） diagnostic criteria and treatment principle （draft）[1] and the ATS （ATS） [2] related guidelines ,diagnosed or treated with antifungal effective 30 patients with pulmonary aspergillus infection were retrospectively analyzed ,mi‐crobiological diagnosis process and consistency and clinical diagnosis .Results Conclusion The incidence of aspergil‐lus microbial results consistent with the results of clinical diagnosis .Pulmonary aspergillus infection has been develo‐ping rapidly ,and relatively high case fatality rate of early when there is no clear indications and clinical diagnosis ,spu‐tum culture and sputum smear positive results of aspergillus can indicate direction to the diagnosis ,accurate and time‐ly diagnosis can promote the success rate of the clinical treatment to improve the patient′s satisfaction ,promote the clinical diagnosis and treatment of pulmonary aspergillosis .

关 键 词：肺部曲霉菌感染 微生物检验 临床诊治 诊断流程 感染患者 肺曲霉菌 支气管灌洗液 美国胸科协会 

分 类 号：R563.1[医药卫生—呼吸系统]