基于“肝脾理论”探讨肠源性内毒素血症致继发性肝损伤  

To Discuss the Secondary Liver Injury Induced by Intestinal Endotoxemia based on "The Liver and Spleen Theory"

作　　者：赵国荣[1] 陈研焰 何宜荣[1] 毛娅男[1] 王志明 肖碧跃[1] 

机构地区：[1]湖南中医药大学,湖南长沙410208 [2]湖南中医药研究院附属医院,湖南长沙410006

出　　处：《湖南中医药大学学报》2016年第1期44-46,共3页Journal of Hunan University of Chinese Medicine

基　　金：湖南省教育厅重点资助项目(12A101);湖南中医药大学中医临床基础重点学科资助

摘　　要：运用中医肝脾理论相关内容剖析肠源性内毒素血症致继发性肝损伤的发生机制及其治疗思路,并从该角度阐述中西医理论内在联系,认为与肠源性内毒素血症致继发性肝损伤相联系,肠道黏膜屏障功能(intestinal barrierfunction,IBF)、胆汁酸的肠肝循环、肝与肠道免疫功能相互依赖、IBF障碍与肝损伤的恶性循环、改善肠道功能以保护肝脏的治疗理念均是肝脾理论现代生物学基础的具体体现。The mechanism and clinical treatment of intestinal endotoxemia induced the secondary liver injury were discussed by using the liver and spleen theory, which explain the inner connection between traditional Chinese medicine and Western medicine. We hold the view that the relation with the secondary liver injury induced by intestinal endotoxemia. The modern biological basis of the liver and spleen theory reflected of medical concepts： enterohepatic circulation of bile acid, interdependence of intestinal and immune function, IBF injury with vicious circle of liver injury, and improving intestinal function to protect liver.

关 键 词：肝脾理论 肠源性内毒素血症 肝损伤 肠-肝轴 肝病实脾 

分 类 号：R2-03[医药卫生—中医学]