间期胃癌的胃黏膜上皮的病理特点  

Pathological characteristics of gastric epithelial mucosa of patients with interval gastric cancer

作　　者：林惠明[1] 张金平[1] 李东颖[1] 李建生[1] 

机构地区：[1]郑州大学第一附属医院消化内科,河南省郑州市450052

出　　处：《世界华人消化杂志》2016年第1期104-108,共5页World Chinese Journal of Digestology

摘　　要：目的:分析间期胃癌的临床病理特征及合适的筛查间期,为临床医生随访诊断早期胃癌检查的时间段提供理论依据.方法:回顾性分析郑州大学第一附属医院2012-01-01/2014-12-31的41例间期胃癌患者的临床及病理特征.比较漏诊胃癌组及潜在胃癌组间的差异及临床意义.结果:41例IGC患者中漏诊胃癌的15例,潜在胃癌的26例.平均年龄为52.56岁±10.60岁,平均间期时间为18.9 mo.IGC组织学表现为中低分化型腺癌的33例(80.5%),位于胃窦的18例(43.9%),胃镜下表现为溃疡型的24例(58.5%).结论:间期胃癌主要为位于胃窦部的大体表现溃疡型的未分化型腺癌.漏诊胃癌组的患者通常比潜在胃癌组的患者年轻.合适的内镜筛查间期为不超过3年.AIM： To evaluate the clinicopatholog i ccharacteristics of interval gastric cancer（IGC） and the optimal frequency of endoscopy for gastric cancer screening.METHODS： A retrospective analysis was performed of 41 patients with interval gastric cancer treated at the First Affiliated Hospital of Zhengzhou University from January 1, 2012 to December 31, 2014. We compared the differences between the missed cancers and the latent cancers. RESULTS： A total of 41 IGC patients were identif ied, with a mean age of 52.56 years ± 10.60 years and a mean interval time of 18.9 mo. There were 33 IGC patients with poorly differentiated adenocarcinoma（80.5%）, 18 IGC patients with tumor located in the gastric antrum（43.9%）, and 24 IGC patients exhibited endoscopic ulcer morphology（58.5%）. CONCLUSION ： IGCs tend to be poorly differentiated, located in gastric antrum and exhibit endoscopic ulcer morphology. The optimal frequency of endoscopy for gastric cancer screening may be 3 years. The patients with missed cancer are generally younger than the patients with latent cancer.

关 键 词：间期胃癌 漏诊胃癌 潜在胃癌 组织病理学 

分 类 号：R735.2[医药卫生—肿瘤]