普萘洛尔治疗婴幼儿血管瘤的并发症分析  

Analysis of the complications in patients with infantile hemangiomas treated by oral Propranolol

作　　者：汪城河[1] 苏振民[1] 林文雄[1] 黄曲惠[1] 吴雅莹[1] 刘长江[1] 

机构地区：[1]福建医科大学教学医院泉州市儿童医院,妇幼保健院整形外科,福建泉州362000

出　　处：《中国美容医学》2016年第1期54-56,共3页Chinese Journal of Aesthetic Medicine

摘　　要：目的:分析口服普萘洛尔治疗婴幼儿血管瘤的并发症,评估其安全性及治疗效果。方法:回顾分析2011年2月-2013年12月笔者科室收治的213例婴幼儿血管瘤口服普萘洛尔治疗的临床资料。结果:观察患儿心率及血压波动在可耐受范围内,57例(26.8%)患儿出现血糖下降(最低者2.1mmol/L,平均3.31mmol/L),其中并发多次血糖下降者30例(14.1%);其他并发症:有睡眠改变47例(22.1%)、食欲下降29例(13.6%),大便性状改变者53例(24.9%)。绝大多数患儿获得满意的临床疗效,出现并发症多为暂时且无明显后遗症。结论:口服普萘洛尔治疗婴幼儿血管瘤安全性较高,且可获得满意疗效。Objective To analyze the complications the oral propranolol treatment for infantile hemangioma, assess therapeutic safety and curative effect. Methods To review the chinical data of that Oral propranolol was applied to 213 cases with infantile hemangiomas（IH） in Quan zhou Children Hospital,Department of Plastic Surgery from February 2011 to December 2013. Results The heart rate and blood pressure fluctuated in the tolerable range.There were 57 patients（26.8%）decreased in glucose of blood（the average tendency for 3.31 mmol / L, the lowest for 2.1mmol / L）,and 30 cases taken place more than once.Other side effects included sleep changes（47 cases,22.1%）,inappetence（29 cases,13.6%）,and the change of character of stool（53 cases,24.9%）.The vast majority of infants had obtained satisfactory clinical efficacy, and the complications were temporarily without obvious sequelae. Conclusion Oral propranolol treatment is an effective method for IH,and can obtain satisfactory curative effect.

关 键 词：血管瘤 普萘洛尔 并发症 后遗症 疗效 

分 类 号：R732.2[医药卫生—肿瘤]