Onyx胶栓塞治疗颌面部动静脉畸形的临床研究  

Embolotherapy with Onyx for maxillofacial arteriovenous malformations

作　　者：任伟超[1] 孙成建[1] 王彦华[1] 刘彤晖[1] 解玲玲[1] 王承恩[1] 

机构地区：[1]青岛大学附属医院介入医学科,山东青岛266003

出　　处：《中国耳鼻咽喉头颈外科》2016年第1期19-22,共4页Chinese Archives of Otolaryngology-Head and Neck Surgery

摘　　要：目的探讨Onyx胶在栓塞治疗颌面部动静脉畸形的疗效与安全性。方法 2013年2月~2014年5月我科收治颌面部动静脉畸形患者16例,畸形血管团位于下颌8例,上颌5例,眶周3例,对所有患者均采用Onyx胶液体栓塞剂进行栓塞治疗并随访,根据造影显示的畸形血管团血流状况评价栓塞疗效。结果栓塞后即时造影显示3例完全栓塞,10例50%~90%栓塞,3例栓塞〈50%,总有效率81.25%（13/16）。1例患者术后出现短暂性视力下降20 d后恢复,无永久性视觉异常出现。13例患者胀痛、发热症状消失,2例缓解,1例较前加重,无出现皮肤坏死患者;6个月后血管造影随访,2例畸形血管团较前有所增大,余均稳定。结论 Onyx胶在颌面部动静脉畸形的栓塞是一种安全、有效的治疗方法,近期疗效确切,远期疗效有待于进一步跟踪评价。OBJECTIVE To discuss the efficacy and safety of Onyx embolization for the treatment of maxillofacial arteriovenous malformation（mAVMs）.METHODS Between February 2013 to May 2014,16 patients with mAVMs received embolotherapy in our department.Eight cases＇ mAVMs located in mandibular region,5 cases located in the maxillary region and the other3 cases located near the orbital region.Embolotherapy with Onyx was carried out in all patients and all the patients were followed-up.The effect of embolization was evaluated according to the deformity arteriolar blood flow.RESULTS After the embolization,angiograpy showed that complete occlusion of mAVMs was achieved in 3 cases,50%-90%occlusion in 10 cases,50%occlusion in 3 cases,and the overall response rate was 81.25%（13/16）.After operation,temporary decreased vision was obtained in one patient and recovered after 20 days,no permanent visual abnormality was found in all of the cases.Complications as distending pain,fever disappeared in 13 patients,improved in 2 patients and became worse in one patient.There was no case of skin necrosis occurred.Follow-up for 6 months after treatment,the deformity arteriolar blood flow larger than before was found in 2 cases and the others were stable.CONCLUSION Onyx embolization for the treatment of maxillofacial arteriovenous malformation is a safe and effective method,the short term curative effect has been confirmed while the long term curative effect should be further evaluated.

关 键 词：动静脉畸形 栓塞 治疗性 颌面部 ONYX 

分 类 号：R782[医药卫生—口腔医学]