地塞米松联用甘露醇治疗感染性脑水肿临床效果观察  

Clinical Observation Effect of Hexadecadrol Combine With Mammitol in Treatment of Infectious Encephaledema

作　　者：吴松伟 

机构地区：[1]河南省南阳市镇平县人民医院神经内科,474250

出　　处：《中国继续医学教育》2016年第2期155-156,共2页China Continuing Medical Education

摘　　要：目的观察地塞米松联用甘露醇治疗感染性脑水肿的临床效果。方法选择2013年6月-2014年7月来我院治疗感染性脑水肿的患儿128例,随机将其分成对照组和治疗组,每组64例。对照组采用速尿加甘露醇治疗,治疗组采用地塞米松加甘露醇治疗,观察两组患儿治疗效果。结果两组患儿在脑脊液TNF-α、IL-1、NO水平、病死率及后遗症发生率方面相比,P〈0.05,差异具有统计学意义。结论对感染性脑水肿患儿采用地塞米松联用甘露醇共同治疗效果明显,能有效降低病死率及后遗症的发生率,改善患儿生活水平,临床可将地塞米松作为治疗感染性脑水肿的有效药物。Objective To observe the clinical effect of dexamethasone combined with mannitol in treatment of infectious cerebral edema.Methods Selected 128 children with infectious brain edema from June 2013 to July 2014 in our hospital were randomly divided into control group and treatment group,each group had 64 cases.The control group using furosemide and mannitol treatment,the treatment group were treated with dexamethasone plus mannitol treatment,observed the therapeutic effect of two groups.Results There were significant differences in the levels of,IL-1,TNF-α,NO,and the incidence of complications in the two groups（P〈0.05）.Conclusion The treatment effect of dexamethasone combined with mannitol in children with infectious cerebral edema is obvious,and it can effectively reduce the incidence of mortality and sequelae,improve the living standard,and can be used as an effective drug for treatment of infectious brain edema.

关 键 词：地塞米松 甘露醇 感染性脑水肿 治疗效果 

分 类 号：R742[医药卫生—神经病学与精神病学]