丁苯酞氯化钠注射液对低血糖后脑梗死患者血管内皮功能的影响  

The Effection of Butyl Phthalide and Sodium Chloride Injection for Vascular Endothelial in Patients with Hypoglycemia Afterbrain Infarction

作　　者：牛慧艳[1] 张占强[1] 李彦[1] 郭立军[1] 谢志领 韩杰[1] 王海[1] 

机构地区：[1]河北省涿州市医院神经内科,河北保定072750

出　　处：《糖尿病新世界》2015年第23期30-32,共3页Diabetes New World Magazine

基　　金：丁苯酞注射液对炎性因子的影响;编号:14ZF013。恩必普在缺血性脑卒中二级预防中的安全性及有效性;编号:2011BA108B03。(国家"十二五"科技支撑计划项目)

摘　　要：目的分析丁苯酞氯化钠注射液对低血糖后脑梗死患者血管内皮功能(VEGF)的影响。方法选择64例急性低血糖后脑梗死患者,按NIHSS评分随机分为治疗组和对照组,在基础治疗相同的情况下,分别在治疗前及治疗后1 d、7 d、14 d测两组的NIHSS评分及血管内皮生长因子VEGF(ng/L)。结果治疗前两组NIHSS、VEGF无明显差异(P>0.05),治疗后治疗组NIHSS评分显著低于对照组而VEGF明显高于对照组(P<0.05)。结论丁苯酞氯化钠注射液在低血糖诱发的急性脑梗死治疗中通过改善血管内皮生长因子而改善脑梗死。Objective To analyze butyl phthalide and sodium chloride injection on the vascular endothelial function of pa-tients with hypoglycemia afterbrain infarction （VEGF）. Methods Select 64 cases of acute hypoglycemia afterbrain infarction patients, according to the NIHSS scores were randomly divided into treatment group and control group, in the foundation treatment of the same case, respectively before and after treatment 1 day, 7 days, 14 days of two groups of NIHSS score and vascular endothelial growth factor （VEGF （ng/L）. Results The two groups before treatment NIHSS, VEGF, no significant difference （P〉0.05）, treatment group after treatment NIHSS score was significantly lower than the control group and VEGF are significant-ly higher than control group （P〈0.05）. Conclusion Butyl phthalide and sodium chloride injection in hypoglycemia induced acute cerebral infarction by improving vascular endothelial growth factor in treatment and improve the cerebral infarction.

关 键 词：低血糖 脑梗死 丁苯酞氯化钠注射液 血管内皮生长因子 

分 类 号：R74[医药卫生—神经病学与精神病学]