显微外科手术治疗颅咽管瘤95例预后分析  

Analysis of related factors for survival and microneruosurgical treatment of craniopharyngioma

作　　者：李志鹏[1] 吴鹏飞[1] 王运杰[1] 

机构地区：[1]中国医科大学附属第一医院神经外科,辽宁沈阳110002

出　　处：《临床军医杂志》2015年第5期450-452,共3页Clinical Journal of Medical Officers

基　　金：国家青年自然科学基金(81001124)

摘　　要：目的探讨颅咽管瘤显微手术治疗的方法选择及影响患者预后的相关因素。方法回顾性分析2008年1月至2013年6月中国医科大学附属第一医院收治的95例颅咽管瘤患者临床资料,均行显微外科手术治疗。随访并评估生存质量。结果肿瘤全切除70例,次全切除15例,部分切除10例。最常见的术后并发症为垂体功能低下及尿崩。术后随访8个月至5年,死亡16例(16.8%),复发14例。性别和切除程度是影响术后5年生存率的危险因素。结论采用显微外科手术全切颅咽管瘤,5年生存率较高,且复发率较低。Objective To investigate the optimal management of craniopharyngioma and related factors for patients survival. Methods A retrospective analysis and long-term follow-up were carried out in 95 cases who underwent microsurgery of craniopharyngioma from2008 Jan. to 2013 Jun. Results Total tumor resection was achieved in 70 cases,subtotal resection in 15 cases,partial resection in10 cases. The most common complications after surgery for pituitary dysfunction and diabetes insipidus. Patients were followed up for8 months to 5 years after operation. 16 patients died during the follow-up period（ 16. 8%）,recurrence in 14 cases. Postoperative survival rate related with operation methods and the gender of the patient. Conclusion The microsurgical total resection of craniopharyngioma had better survival rate and lower recurrence rate.

关 键 词：颅咽管瘤 显微外科手术 手术入路 

分 类 号：R739.41[医药卫生—肿瘤]