2012年山东省主要恶性肿瘤疾病负担评价  

Evaluation of Disease Burden of Primary Malignant Tumors in Shandong Province in 2012

作　　者：董惠玲[1] 杨瑞贞[1] 赵飞燕[1] 王媛媛[1] 吴炳义[1] 

机构地区：[1]潍坊医学院护理学院,山东潍坊261053

出　　处：《中国肿瘤》2016年第1期20-24,共5页China Cancer

基　　金："健康山东"重大风险预测与治理协同创新中心重点项目(XT1403002);潍坊医学院科技创新基金项目(K1301019)

摘　　要：[目的]分析2012年恶性肿瘤对山东省居民造成的疾病负担,比较健康评价指标的差别。[方法]采用伤残调整生命年(DALY)评价主要恶性肿瘤的疾病负担,并与发病率和死亡率进行比较。[结果]2012年山东省恶性肿瘤发病率为261.92/10万(标化率为171.9/10万),死亡率为175.3/10万(标化率为144.5/10万),男性恶性肿瘤标化发病率的死亡率均明显高于女性。YLD率与发病率相比,各类恶性肿瘤的顺位相差较大;DALY率与死亡率相比,各类恶性肿瘤的顺位变化较小。肺癌、肝癌、胃癌居男女性恶性肿瘤DALY率的前三位,但女性生殖系统的恶性肿瘤疾病负担高于男性。山东省恶性肿瘤的疾病负担主要由早死所致,且主要集中于45岁以上的中老年人群。[结论]DALY可综合反映早死与伤残两种健康后果的疾病负担,为公共卫生领域准确把握影响人口健康的重大风险、明确疾病预防控制工作战略重点提供科学依据。[Purpose] To analyze the disease burden caused by the residents of Shandong province in 2012,in order to compare the differences of the health evaluation indexes. [Methods] Disability adjusted life year（DALY） was used to evaluate the disease burden of primary malignant tumors and to compare with incidence and morbidity. [Results] The incidence of malignant tumor in Shandong province in 2012 was 261.92/10~5,and the mortality of malignant tumor was 175.3/10~5. Standardized mortality and incidence for male were significantly higher than those for female. Compared with the incidence of malignant tumors,the position for YLD rate changed significantly.Compared with the mortality,the position for changed little DALY rate. Malignant tumor DALY rate of lung cancer,hepatocellular carcinoma,gastric cancer ranked in the top three both in male and female. However the burden of malignant tumor of the female reproductive system was significantly higher than that in male. Malignant tumor in Shandong province disease burden mainly caused by premature death,and mainly concentrated at the age of 45 and above. [Conclusion]DALY can reflect the disease burden of premature death and disability,in order to provide scientific basis on which accurately to grasp the significant risks in the field of public health and to clear disease prevention and control work strategy.

关 键 词：恶性肿瘤 疾病负担 DALY 

分 类 号：R73[医药卫生—肿瘤]