老年脂肪肝患病危险因素病例对照研究  

Case-control study on risk factors of fatty liver in elderly people

作　　者：侯桂侠 张素娟[2] 王铭 肖永红 

机构地区：[1]唐山市丰南区中医医院检验科,河北唐山063700 [2]唐山市妇幼保健院,河北唐山063000 [3]华北理工大学公共卫生学院,河北唐山063009

出　　处：《职业与健康》2016年第1期88-90,共3页Occupation and Health

摘　　要：目的探讨老年脂肪肝患病危险因素,为脂肪肝防治提供科学依据。方法选择某县2014年进行健康检查的60岁以上的老年人群,采用病例对照研究方法,应用单因素和多元logistic回归统计方法分析老年脂肪肝患病的影响因素。结果多因素Logistic回归分析表明,饮酒、体重指数(BMI)、空腹血糖(FPG)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)是老年脂肪肝的危险因素,而高密度脂蛋白胆固醇(HDL-C)为脂肪肝保护因素;进一步相关分析显示,老年脂肪肝患者BMI与FPG、TC、TG、LDL-C均呈显著正相关(P<0.05),与HDL-C呈显著负相关(P<0.05)。结论老年脂肪肝与肥胖、饮酒及糖代谢、脂代谢紊乱密切相关。[Objective]To explore the risk factors of fatty liver in elderly people, provide scientific basis for prevention and control of fatty liver. [Methods]The elderly people（ over 60 years old） who have received health examination in a county in 2014 were collected. The case-control study method was adopted, and the risk factors of fatty liver in elderly people were analyzed by the single factor and multiple logistic regression.[Results]The multiple logistic regression analysis showed that alcohol drinking, body mass index（ BMI）, fasting blood glucose（ FPG）, total cholesterol（ TC）, triglyceride（ TG） and low density lipoprotein cholesterol（ LDL-C） were the risk factors of fatty liver in elderly people, while the high density lipoprotein cholesterol（ HDL-C） was the protection factor. The correlation analysis revealed that BMI was positively correlated with FPG, TC, TG and LDL-C（ P〈0.05）,and there was a significantly negative correlation between BMI and HDL-C（ P〈0.05）.[Conclusion]The fatty liver in elderly people is closely related to obesity, alcohol drinking, glucose metabolic disorder and lipid metabolic disorder.

关 键 词：老年 脂肪肝 患病 危险因素 

分 类 号：R575.5[医药卫生—消化系统]