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作 者:张晓玲[1] 翟丽萍[1] 官俏兵[1] 陈中栋[1] 王琰萍[1] 朱敏初[1]
机构地区:[1]浙江省嘉兴学院附属第二医院神经内科,314000
出 处:《中华老年医学杂志》2016年第2期159-162,共4页Chinese Journal of Geriatrics
基 金:浙江省医药卫生一般研究计划(2013KYB260);浙江省医学会新晨神经内科科研专项(20122YC-A64)
摘 要:目的观察老年帕金森病(Parkinson’S disease,PD)伴慢性疼痛患者的临床特征。方法收集366例原发性PD伴疼痛患者,依据年龄分为老年组289例和非老年组77例,进行视觉模拟评分(VAS)、统一PD评定量表(UPDRS)、Hoehn-Yahr(H—Y)分期、焦虑自评量表(SAS)、抑郁自评量表(SDS)、简易疼痛量表(BPI)等评估。结果老年PD伴疼痛患者UPDRSⅡ、Ⅲ、Ⅳ、H—Y分期、VAS和BPI的子项13常生活、工作、睡眠、行走能力及社交评分分别为(13.7.4±5.3)分、(27.3±12.9)分、(2.3±2.2)分、(2.4±1.0)期、(63.3±25.6)分、(5.3±2.7)分、(5.9±3.2)分、(6.3±2.5)分、(4.7±3.1)分、(3.2±2.1)分,高于非老年PD伴疼痛患者(12.3±6.3)分、(23.3±9.6)分、(1.7±1.3)分、(2.1±0.9)期、(56.6±25.0)分、(4.6±2.7)分、(5.1±2.8)分、(5.6±2.6)分、(3.8±2.0)分、(2.6±2.5)分,差异均有统计学意义(t=1.976、2.539、2.287、2.381、2.050、2.021、1.997、2.165、2.420、2.134,均P〈0.05);两组患者SAS、SDS和BPI另2个子项生活乐趣和情绪评分差异无统计学意义(均P〉0.05);老年PD患者伴疼痛组存在2种及以上PD相关疼痛类型的比率41.2%(119例),较非老年组23.4Yoo(18例)更高,但接受相关疼痛治疗的比率更少[29.8%(86例)比51.9%(40例)](χ2=8.190、13.260,均P〈0.05)。结论老年PD伴疼痛患者疼痛程度重,与PD相关的疼痛类型多,生活质量受影响,应加强对该人群的干预治疗。Objective To analyze the clinical features of Parkinson's disease (PD) combined with chronic pain in the elderly. Methods A total of 366 idiopathic PD patients experiencing pain were enrolled and divided into two groups: the elderly group (n: 289) and the young group (n= 77). Rating scales including Visual Analogue Scale (VAS), Unified Parkinson's Disease Rating Scale (UPDRS), Hoehn Yahr (H-Y) Scale, SelFrating Anxiety Scale (SAS), Self-rating Depression Scale (SDS) and Brief Pain Inventory (BPI) were evaluated. Results Compared with the young group, the elderly group had evidently higher scores of UPDRS11 , 1H , IV, H-Y Scale, VAS as well as five sub-items of BPI including daily living, working, sleeping, walking ability and social communication ((13.7±5.3) v.v (12.3±), (27.3±12.9)vs.(23.3±.6), (2.3±2.2)vs(1.7±1.3), (2.4±1.0)vs (2.1±0. 9) , (63. 3±25. 6) w (56.6±25.0), (5.3±2.7)v,v (4.6±), (5.9±3.2)vs. (5. 1±2.8), (6.3±2.5)vx (5.6±2.6), (4. 7±3.1) vs (3.8±2.0), (3.2±2.1)vs. (2.6±.5), t=1.976, 2.539, 2.287, 2.381, 2.050, 2.021, 1.997, 2.165, 2.420, 2.134, respectively, all P〈0. 051. No significant differences were found in SAS, SDS or other sub-items of BPI such as life pleasure and mood scores between the two groups (all P〈0.05). Compared with the young group, patients in the elderly group had a higher ratio of two or more pain types associated with PD(41.2% (119/299)w 23.4% (18/77), χ2=8. 190, P〈0.05), but a lower ratio of pain-related treatment(29.76% (86/299)w 51.95% (40/77), χ2 =13. 260, P〈0. 051. Conclusions Pain in elderly PD patients is more severe , shows more diverse types, and significantly affects the quality of life. Enhanced intervention is needed.
分 类 号:R742.5[医药卫生—神经病学与精神病学]
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