393例肺癌患者的电子支气管镜检查结果分析  

Analysis of results of electronic bronchoscopy in 393 patients with lung cancer

作　　者：王晓平[1,2] 陈利军[1] 万毅新[1] 陶红艳[1] 黄晖蓉[1] 武凡祺[1] 张丽[1] 倪京满[2] 

机构地区：[1]兰州大学第二医院,甘肃兰州730000 [2]兰州大学药学院,甘肃兰州730000

出　　处：《中国生物制品学杂志》2016年第2期175-180,共6页Chinese Journal of Biologicals

摘　　要：目的分析393例肺癌患者的电子支气管镜检查结果,探讨电子支气管镜在肺癌诊断中的价值。方法对兰州大学第二医院2012~2014年的393例肺癌患者的病历进行回顾性分析,采用SAS 9.3统计软件进行数据统计学分析。结果肺癌的分布右肺多于左肺,上叶多于下叶。393例肺癌患者中,284例镜下表现为管内增殖型,47例管壁浸润型,8例管外压迫型,33例炎症型,18例混合型,3例镜下未见明显异常。其中钳检阳性率94.10%,刷检阳性率60.71%,两者差异有统计学意义（P〈0.000 1）;鳞癌和小细胞癌钳检的阳性率为96.84%和97.67%,均明显高于腺癌（P〈0.000 1）,小细胞癌刷检阳性率明显高于腺癌（P〈0.05）,小细胞癌与鳞癌刷检阳性率差异无统计学意义（P〉0.05）,鳞癌和腺癌刷检阳性率差异无统计学意义（P〉0.05）。中央型肺癌钳检阳性率（95.72%）高于周围性肺癌（P〈0.000 1）,中央型肺癌和周围性肺癌刷检阳性率差异无统计学意义（P〉0.05）。结论电子支气管镜检查具有确诊率高、创伤小及安全性高等优点,是目前肺癌确诊的重要检查方法。Objective To analyze the results of electronic bronchoscopy in 393 patients with lung cancer and investi- gate the role of electronic bronchoscopy in diagnosis of lung cancer. Methods The data on 393 patients with lung cancer in 2012 - 2014 in the Second Hospital of Lanzhou University were analyzed retrospectively, and subjected to medical statistic analysis by using SAS 9. 3 software. Results The lung tumors were distributed more in right lung than in left lung, and more in lobi superior than in lobi inferior. Of the 393 cases of lung cancer, 284 cases were of neoplasm type, 47 cases of invasive type, 8 cases of outer suppression type, 33 cases of inflammation type, and 18 cases of neoplasm with invasive type under bronehoscope, while no obvious abnormalities were observed in 3 cases. The positive rates in biopsy and brushing examination were 94.10% and 60. 71% respectively, which showed significant difference （P 〈 0. 000 1 ）. The positive rates of squamous cell carcinoma and small cell cancer in biopsy were 96. 84% and 97. 67% respectively, which were significantly higher than those of adenocarcinoma （P 〈 0. 000 1 ）. However, the positive rate of small cell cancer in brushing examination was significantly higher than that of adenocarcinoma （P 〈 0. 05 ） while showed no significant difference with that of squamous cell carcinoma （P 〉 0. 05）. The positive rates of squamous cell carcinoma and adenocarcinoma in brushing examination showed no significant difference （P 〉 0. 05）. The positive rate of central type carcinomas in biopsy （95. 72%） was higher （P 〈 0. 000 1 ） than, while that in brushing examination showed no significant difference with, that of peripheral type carcinomas （P 〉 0. 05）. Conclusion Electronic bron- choscopy showed high confirmation rate, less trauma and high safety, which was an important method for diagnosis of lun~ cancer.

关 键 词：肺癌 电子支气管镜 

分 类 号：R734.2[医药卫生—肿瘤] R443.8[医药卫生—临床医学]