γ-聚谷氨酸在生物制品中应用的研究进展  

Progress in study on application of γ-glutamic acid in biological products

作　　者：宋小锋[1] 原增艳[1] 许平辉 

机构地区：[1]新乡医学院三全学院,河南新乡453003 [2]新乡市辉隆生物科技有限公司,河南新乡453300

出　　处：《中国生物制品学杂志》2016年第2期221-224,共4页Chinese Journal of Biologicals

摘　　要：γ-聚谷氨酸(poly-γ-glutamic acid,γ-PGA)是一种具有水溶性、生物相容性、生物可降解性、无毒的聚合氨基酸。本文综述了γ-PGA作为原辅料在治疗用生物制品、预防用生物制品和新型生物材料制品中的应用及其作为稳定剂、冷冻保护剂及絮凝剂在生物制品中的应用,同时展望了γ-PGA在诊断用生物制品方面的应用前景。Poly γ-glutamic acid （γ-PGA） is a naturally occurring poly amino acids with characteristics of water solubility, biocompatibility, biodegradability and non-toxicity towards human and the environment. This paper reviews the application of γ-PGA as a raw material in prophylactic and therapeutic biological products and novel biomaterial products and as stabilizer, cryoprotecive agent and flocculating agent in biological products. Meanwhile, the prospect of γ-PGA applied to diagnostic biological products is investigated.

关 键 词：Γ-聚谷氨酸 生物制品 

分 类 号：Q517[生物学—生物化学] R392-33[医药卫生—免疫学]