前列腺癌质子碳离子治疗设备成像系统应用研究  

The application of the proton and carbon ion treatment equipment imaging system in prostate cancer therapy

作　　者：周丹 傅深[2,3] 李萍 姚嘉玺 

机构地区：[1]上海市质子重离子医院放射物理科,201321 [2]上海市质子重离子医院放疗科,201321 [3]复旦大学附属肿瘤医院放疗科,上海200233

出　　处：《中华放射肿瘤学杂志》2016年第2期164-167,共4页Chinese Journal of Radiation Oncology

摘　　要：目的评价质子碳离子治疗设备千伏级x线成像系统对前列腺癌放疗摆位精度。方法选择2014年6—8月接受碳离子治疗的14例前列腺癌患者入组。每次治疗前通过成像系统采集两组正交野图像，与计划DRR图像融合并进行手动＋自动匹配。获得侧向（治疗床面短轴方向）、纵向（治疗床面长轴方向）、垂直（垂直于治疗床面的方向）、等中心旋转（治疗床面沿等中心水平旋转）、横滚（以治疗床面长轴为中心的旋转）、俯仰（以治疗床面短轴为中心的旋转）方向摆位误差数据。分析数据探讨成像系统在碳离子治疗前列腺癌中的使用情况。结果14例患者共获得644组图像。6个方向误差均值分别为0．34cm、0．30cm、0．79cm、0．3°、0．5°、1．1°。误差随着分次无明显变化，两组拍片获得的误差也无差异，但俯仰和垂直方向上的误差值较大。结论正交野图像的骨性标志清晰，拍片时间短，DRR参考图像为三维的，可获得6个方向上位置误差。但软组织成像差，获得的数值不能完全等同于前列腺癌患者治疗时的真实误差。Objective To evaluate the accuracy of the patient positioning in prostate cancer therapy with the kilo-voh X-ray imaging system. Methods From June to August in 2014,14 patients with prostate cancer were treated by carbon ion beam with the Siemens proton and carbon ion equipment. X-ray orthogonal images was made twice by the imaging system before treatment. All the images were fused with the planning digitally reconstructed radiograph ones by automatic and manual method. We got positioning error data in six directions： lateral, longitudinal, vertical, isocentre, roll and pitch. The data were analyzed to study the situation. Results A total of 644 pairs of images from 14 patients were obtained during treatment. The average error in six directions is 0. 34 cm,0. 30 cm,0. 79 cm,0. 3°, 1.1° and 0. 5°.The patients＇ positioning error had no obvious change in all directions with fractions. There was no significant deviation between the two groups of images, either. But error in pitch and vertical direction is much larger. Conclusions The bony landmarks of the orthogonal filed images are clear. Photography lasts short time by the imaging system. DRR images are 3D and we can get images in six directions,but the development of soft tissue is weak. Positioning error we get cannot be match with the one of actual situation.

关 键 词：碳离子 前列腺癌 成像系统 正交野 

分 类 号：R737.25[医药卫生—肿瘤]