百年老药苯巴比妥治疗癫的临床应用进展  

A classic drug phenobarbital and its application progress in treating epilepsy

作　　者：王晓玮[1] 王文志[1] 茹小娟[1] 

机构地区：[1]首都医科大学北京市神经外科研究所临床流行病学北京市重点实验室,100050

出　　处：《中国现代神经疾病杂志》2016年第1期47-51,共5页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：中央补助地方卫生事业专项基金资助项目[财社(2004)24号]~~

摘　　要：苯巴比妥作为传统抗癫药物在临床应用已逾百年,至今仍在世界范围内广泛应用。作为世界卫生组织推荐的发展中国家治疗和控制癫发作的一线药物,苯巴比妥能够有效缩小治疗缺口。本文对苯巴比妥在世界范围内的应用情况、疗效及其相关药物不良反应的研究进展进行概述。As a classic antiepileptic drug（AED）, phenobarbital has been used in clinic for morethan 100 years and is available in the majority of countries in the world. Accepted as the drug of choicefor controlling seizures in developing countries by World Health Organization（WHO）, phenobarbital caneffectively lessen the treatment gap. In this paper, the utilization of phenobarbital around the world, and itscurative effect and adverse drug reaction were reviewed.

关 键 词：苯巴比妥 癫 综述 

分 类 号：R742.1[医药卫生—神经病学与精神病学]