先天性白内障大鼠的血压与体温基础数据分析  

Correlation analysis on the blood pressure and body temperature of congenital cataract rat

作　　者：田小芸[1] 尤金炜[1] 董敏[1] 方天[1] 刘捷[1] 恽时锋[1] 

机构地区：[1]南京军区南京总医院比较医学科,南京210002

出　　处：《中国比较医学杂志》2016年第1期54-57,共4页Chinese Journal of Comparative Medicine

基　　金：南京总医院基金(2011001)

摘　　要：目的为了完善先天性白内障大鼠的背景资料,对该大鼠的血压与体重及体温进行了测定,并进行相关性分析。方法分别取三个体重段的正常睑裂白内障大鼠、小眼白内障大鼠和正常对照SD大鼠各30只,雌雄各半,用多道生理信号采集系统进行实验。结果三个体重段雌雄大鼠的血压间无统计学意义(P>0.05),但随着体重的增加,血压与体重之间逐渐形成相关关系;同品系雄性大鼠标准体重与老龄大鼠血压间有统计学意义(P<0.01)。各体重段雌雄大鼠体温有统计学意义(P<0.01),且雄性体温均低于雌性。结论白内障大鼠的血压、体重和体温的变化符合大鼠的生理特性,为今后该鼠的使用提供理论基础。Objective To optimize the background of the congenital cataract in rats,the blood pressure,body temperature and weight of rats were measured and correlation analysis. Methods We took three kinds of rats（ cataracts rat,microphthalmos cataracts rat and normal rat） as subjects,each kind with half males and females was divided into three groups by weight,each of which contains 30 rats. We used the Multi-channel physiological signal acquisition system for test. Results Blood pressure has no significant difference among the three segments of male and female rats（ P〉 0. 05）.With the increase of body weight,blood pressure and body weight formed a relevant relationship gradually. In the same male strain,there was significant difference between the standard weight（ 207 g） and the aging weight（ 494 g）（ P 〈0. 01）. In the same body weight range,the temperature difference between male and female rats was significant（ P 〈0. 01）,and the male＇s temperature was lower than the female. Conclusions The changes in blood pressure,body weight and temperature of cataract rats conformed to the physiological characteristics of rats,which provide a theoretical basis for the use of catatacts rats in the future

关 键 词：先天性白内障 大鼠 血压 体温 相关分析 

分 类 号：R-332[医药卫生]