电感耦合等离子体原子发射光谱-质谱联用法测定中药石菖蒲中的元素  

Determination of metals in Acori Tatarinowii Rhizoma by inductively coupled plasma atomic emission spectrometry-mass spectrometry

作　　者：陈练[1,2] 王利兵[2] 吕小园[2] 贺鹏[2] 颜鸿飞[2] 黎继烈[1] 

机构地区：[1]中南林业科技大学生命科学与技术院,长沙410004 [2]湖南出入境检验检疫局检验检疫技术中心,国家食品安全检测重点实验室,食品安全科学技术湖南省重点实验室,长沙410004

出　　处：《食品安全质量检测学报》2016年第1期124-130,共7页Journal of Food Safety and Quality

基　　金：国家科技支撑计划项目(2012BAD29B05)~~

摘　　要：目的建立中药材中多元素的电感耦合等离子体原子发射光谱-质谱联用法,对中药石菖蒲中的元素进行分析研究。方法运用微波消解进行前处理,电感耦合等离子体原子发射光谱-质谱联用技术结合内标元素校正系统漂移和基体抑制效应,外标法定量。同时运用标准物质、加标回收、精密度试验等进行方法学验证,并运用于中药石菖蒲的元素分析。结果成功运用该方法检测出石菖蒲中的32种元素。方法回归曲线相关系数大于0.995,回收率在80%~110%之间,相对标准偏差小于10%。结论该方法快速、稳定、检出限低、回收率好,可用于中药石菖蒲元素分析。Objective To establish a method for the determination of elements in Chinese traditional medicine Acori Tatarinowii Rhizoma by inductively coupled plasma atomic emission spectrometry-mass spectrometry （ICP-AES/MS）. Methods Based on microwave digestion as pre-treatment, the samples were detected by inductively coupled plasma atomic emission spectrometry-mass spectrometer, adjusted system shift and matrix depression by internal standard element and quantified by external standard method. The validation of method was proved with data of standard material, spiked recoveries and precisions. The method was further used to analyze the elements of Acori Tatarinowii Rhizoma. Results Totally 32 metals in Acori Tatarinowii Rhizoma were detected by ICP-AES/MS. The correlation coefficients of regression equations were more than 0.995. The recoveries were between 80% and 110%, and relative standard deviations were less than 10%. Conclusion The method is fast, stable, and has a low detection limit and good recovery, which can be used for the analysis of metals in Chinese traditional medicine Acori Tatarinowii Rhizoma.

关 键 词：中药 石菖蒲 元素 电感耦合等离子体原子发射光谱-质谱法 

分 类 号：R284.1[医药卫生—中药学] O657.63[医药卫生—中医学]