胃肠间质瘤的临床治疗分析  

Analysis of clinical treatment for gastrointestinal stromal tumors

作　　者：赵期康[1] 陈建飞[1] 刘京山[1] 

机构地区：[1]北京大学首都钢铁公司医院普外科,100144

出　　处：《临床外科杂志》2016年第1期34-35,共2页Journal of Clinical Surgery

摘　　要：目的总结胃肠间质瘤的临床特点和治疗体会。方法胃肠间质瘤患者21例,均行手术治疗,术后行病理及免疫组织化学检查,中、高危患者术后口服伊马替尼靶向治疗。结果 21例患者术后病理检查提示良性9例,12例潜在恶性或恶性,属中、高危患者,口服伊马替尼可提高生存率。结论手术是胃肠间质瘤的主要治疗方法,靶向药物具有延缓胃肠间质瘤复发和转移的作用。Objective clinical characteristics To investigate the of diagnosis and therapeutic strategies of gastrointestinal stromal tumors（GIST）. Methods A total of 21 patients with GIST received surgical treatment and following pathological and immunochemical examinations. The patients in intermedi- ate and high risks were treated with imatinib after surgical resection. Results Pathology showed 9 cases of benign lesions and 12 cases of potential malignant or malignant lesions. Oral imatinib may significantly improve the survival rate of patients in middle and high risks. Conclusion Surgery is the main treatment method for GIST, and targeted drugs for preventing the recurrence and metastasis of tumor have certain clinical significance.

关 键 词：胃肠间质瘤 免疫组织化学 治疗方法 

分 类 号：R735[医药卫生—肿瘤]