白细胞介素23与肝脏疾病的关系  

Research progress in association between interleukin-23 and liver diseases

作　　者：鲍素霞 郑建铭[1] 施光峰[1] 

机构地区：[1]复旦大学附属华山医院感染科,上海200040

出　　处：《临床肝胆病杂志》2016年第2期393-396,共4页Journal of Clinical Hepatology

基　　金：国家十二五重大科技专项(2012zx10002003;2013zx10002004);国家自然科学基金资助项目(81101240;81371821)

摘　　要：白细胞介素(IL)23是近年来发现的细胞因子,越来越多的证据表明其在自身免疫性及炎症性疾病等的发生、发展过程中发挥着重要作用。近年来,国内外在IL-23与肝脏疾病的关系研究取得了一定进展。简述了IL-23的一般性质及生物学特性;对IL-23在乙型肝炎、丙型肝炎和肝细胞癌等疾病发生、发展中的作用进行了综述,以期临床医生对IL-23在肝脏疾病中的作用有更加深入的了解,未来能够为肝病患者提供更优化的治疗。Interleukin 23 （ IL - 23 ） is a recently discovered cytokine, and growing evidence suggests that IL - 23 plays an important role in the development and progression of autoimmune diseases and inflammatory diseases. In recent years, certain research advances in association between IL - 23 and liver diseases have been achieved at home and abroad. General features and biological characteristics of IL - 23 are de- scribed, and its role in the development and progression of diseases such as hepatitis B, hepatitis C, and hepatoceflular carcinoma is re- viewed here, so that clinicians will have a deeper understanding of the effect of IL - 23 in liver diseases and provide optimized therapies for patients with liver diseases.

关 键 词：肝疾病 白细胞介素23 综述 

分 类 号：R575[医药卫生—消化系统]