宫颈癌根治性调强放疗与4野适形放疗的剂量学对比研究  

Dosimetric planning study comparing intensity-modulated radiotherapy with four-field conformal radiotherapy for the definitive treatment of cervical carcinoma

作　　者：倪晓雷[1] 童远和[1] 邹雄伟[1] 李樟[1] 罗东平[1] 

机构地区：[1]福建医科大学附属龙岩市第一医院放疗科,龙岩364000

出　　处：《福建医药杂志》2016年第1期96-98,F0003,共4页Fujian Medical Journal

基　　金：龙岩市科技计划项目(2013LY56)

摘　　要：目的探讨调强放疗技术在宫颈癌根治性放疗中的临床应用价值。方法选择行根治性放疗的宫颈癌患者20例,处方剂量50.4Gy/28F,分别设计7野调强和4野适形放疗计划,获得靶区和危及器官的剂量数据,进行比较分析。结果与4野适形放疗比较,调强放疗均匀指数较小,适形状指数较高,直肠、膀胱、小肠以及股骨头受高剂量照射的体积较小。结论宫颈癌根治性调强放疗在提升靶区均匀性、适形度和降低正常组织照射剂量方面具有优势。Objective To investigate the clinic advantage of intensity-modulated radiotherapy for definitive treatment of cervical cancer. Methods Twenty definitive treatment of cervical carcinoma were planned using both intensity-modulated radio- therapy plan （IMRT-7F） and four-field conformal radiotherapy plan （CRT-4F）, received a dose of 50. 4 Gy/28F. Dose for tar- get and organs at risk were compared for each patient. Results Compare to CRT-4F, IMRT-7F had a smaller uniformity index and a larger conformity index to target volume. IMRT-7F was associated with a significant reduction in the high dose volume to rectum, bladder, small bo＇wel and femur head. Conclusion The uniformity and conformity of target, the high dose to organs at risk of IMRT-7F plan are better than CRT-4F.

关 键 词：宫颈癌 调强放射治疗 临床剂量学 危及器官 

分 类 号：R737.33[医药卫生—肿瘤]