探讨早期适度液体复苏对急性胰腺炎患者的临床效果  

Clinical effects of early appropriate fluid resuscitation in patients with acute pancreatitis

作　　者：陈启明[1] 熊焕宏[1] 朱思奇[1] 叶凤丽[1] 

机构地区：[1]北京大学深圳医院急诊科,广东深圳518036

出　　处：《胃肠病学和肝病学杂志》2016年第2期223-225,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨早期适度液体复苏对急性胰腺炎患者的临床效果。方法选取2013年1月-2014年1月在北京大学深圳医院收治的100例急性胰腺炎患者。对照组以快速液体复苏方式进行治疗,观察组患者采用适度液体复苏,对临床效果进行分析。结果与对照组患者相比,观察组患者治疗后扩容达标时间、HCT、平均输液速度、液体潴留总量差异有统计学意义(P<0.05)。与对照组患者相比,观察组患者治疗后血清BUN、SCr、AST、ALT、TBIL、AMY及Pa O2差异有统计学意义(P<0.05)。与对照组患者相比,观察组患者治疗后APACHEⅡ评分、机械通气率、心功能不全率、MODS、腹内压、腹内间隔综合征及死亡率差异有统计学意义(P<0.05)。结论液体复苏对急性胰腺炎患者是一种较为有效的方式,但是液体复苏不可短时间内大量输入,需要适度。Objective To investigate the clinical effects of early appropriate fluid resuscitation in patients with acute pancreatitis. Methods One hundred cases of acute pancreatitis were selected from Jan. 2013 to Jan. 2014 in Shenzhen Hospital of Peking University. The control group was treated with fast and high volume fluid resuscitation, the observa- tion group was treated with moderate fluid resuscitation, and the clinical effect was analyzed. Results After treatment, there were significant differences in expansion standard time, HCT, average infusion speed, total liquid retention be- tween control group and treatment group （P 〈 0.05 ）; there were significant differences in serum BUN, SCr, AST, ALT, TBIL, AMY and PaO2 between control group and treatment group （P 〈 0.05） ; there were significant differences in APACHE Ⅱ score, mechanical ventilation rate, the rate of cardiac dysfunction, MODS, intra -abdominal pressure, abdominal compartment syndrome and mortality rates were between control group and treatment group （ P 〈 0.05 ）. Conclusion Fluid resuscitation treatment of acute pancreatitis is the most patient-based treatment programs, moderate fluid resuscitation for patients with acute pancreatitis is suitable.

关 键 词：早期适度液体复苏 急性胰腺炎 临床效果 

分 类 号：R576[医药卫生—消化系统]