深圳地区宫颈上皮内瘤变中高危型HPV感染型别和危险因素分析  

Analysis on Categories and Risk Factors of High-risk HPV Infection in Cervical Intraepithelial Neoplasia in Shenzhen Area

作　　者：李晓燕[1] 罗丽丹[1] 吴桂群[1] 邱桂清[1] 

机构地区：[1]广东省深圳市坪山新区人民医院,广东深圳518118

出　　处：《中国医学创新》2016年第4期5-8,共4页Medical Innovation of China

基　　金：深圳市科技计划项目(2012033830);深圳市坪山新区医疗卫生发展孵化资助项目(201344)

摘　　要：目的:总结深圳地区宫颈上皮内瘤变中高危型HPV(乳头瘤病毒)感染型别,探讨其危险因素。方法:选取2012年10月-2014年10月于本院接受宫颈癌筛查的患者500例作为研究对象,对其宫颈上皮内瘤变中的HPV感染类别进行统计、分析,确定其危险因素。结果:深圳地区最常见的感染类别为HPV16,其次为HPV58、52、33、18,此外,多因素分析结果显示,经济收入低、被动吸烟、人工流产、第一次性生活年龄小为HPV感染的独立危险因素(P<0.05)。结论:HPV感染率随着宫颈细胞学病变级别的增高而增高,深圳地区不同宫颈上皮内瘤变患者中HPV感染类别相对单一,为降低宫颈癌发病率,深圳地区应针对HPV感染的危险因素加强健康宣教工作。Objective： To conclude the categories and risk factors of high-risk HPV （ human papilloma virus ） infection in cervical intraepithelial neoplasia in Shenzhen area.Method： 500 patients who accepted cervical cancer screening in our hospital from October 2012 to October 2014 were selected as the research objects. The Categories of high-risk HPV infection in cervical intraepithelial neoplasia were counted and the risk factors were determined.Result： In Shenzhen, the most common infection category was HPV16 and then were HPV58, 52, 33, 18.What＇s more, as the results of multivariate analysis showed, low income, passive smoking, abortion and the first sexual life at early age were the independent risk factors of HPV infection （ P〈0.05 ） . Conclusion： The infection rate of HPV increases as the level of cervical cytology lesions increases.The HPV infection categories of patients withcervical intraepithelial neoplasia in Shenzhen area are rather simplex.In order to decrease the morbidity of cervical cancer, Shenzhen area shall enhance health education aiming at the risk factors of HPV infection.

关 键 词：深圳地区 宫颈上皮内瘤变 高危型HPV感染 型别 危险因素 

分 类 号：R737.33[医药卫生—肿瘤]