介入技术治疗缺血性脑血管疾病49例疗效观察  

Observation on the clinical value of intervention therapy in the treatment of 49 cases of ICVD

作　　者：卫杰[1] 耿昌明[1] 韦道明[1] 刘洁怡[1] 

机构地区：[1]解放军第八五医院神经内科,上海200052

出　　处：《海军医学杂志》2016年第1期47-50,共4页Journal of Navy Medicine

摘　　要：目的探析介入技术在缺血性脑血管病(ICVD)治疗中的近、远期疗效及其临床价值。方法回顾分析2012年4月至2015年5月在我院接受治疗的110例IVCD患者的临床资料,根据治疗方案的不同将入选者分成单纯药物治疗组(对照组)61例和介入治疗组(观察组)49例。比较2组患者的一般资料、治疗前后的病变血管综合评分以及神经功能缺损评分(NIHSS)。结果 2组患者治疗前的病变血管综合评分及NIHSS比较差异无统计学意义(P>0.05),而治疗后3 d及治疗后12个月差异均有统计学意义(P<0.01);此外,观察组治疗后3 d及12个月时的病变血管综合评分及NIHSS与对照组比较差异有统计学意义(P<0.01)。结论介入技术是治疗ICVD患者的安全、有效方法,其近、远期比单纯药物治疗效果好。Objective To investigate and analyze the near and long-term therapeutic effects of intervention therapy on ische- mic cerebrovascular disease （ICVD） patients and its clinical value. Methods Clinical data of 110 ICVD patients who received treat- ment at our hospital from April 2012 to May 2015 were retrospectively analyzed. In accordance with different regimens, the patients were divided into two groups： the simple drug treatment group （or the control group） （61 cases） and the intervention therapy group （or the observation group） （49 cases）. Then, general medical data, comprehensive evaluation scores before and after the treatment and NIHSS scores were compared between the 2 groups. Results There was no statistical significance in the pathologically affected vessels before therapy, when comparisons were made between the two groups （P 〉 0.05）. However, statistical significance could all be seen in the damaged vessels, after 3 days and 12 months of treatment （P 〉0.05）. In additio^a, statistical significance could also be noted in the therapeutic effect of the damaged vessels at day 3 and month 12, when compared with that before treatment（ P 〈0.01 ）. There was no statistical significance in NIHSS scores detected before therapy for the cerebral infarction patients of the groups（P 〉 0.05）. Statisti- cal significance could all be noticed in NIHSS scores, after 1, 6 and 12 months of therapy（ P 〈 0.01 ）. Conclusion Intervention ther- apy is a safe and effective method for the treatment of ICVD patients, its near and long-term therapeutic effects are superior to those of the pure drug therapy.

关 键 词：介入治疗 缺血性脑血管疾病 脑梗死 

分 类 号：R743[医药卫生—神经病学与精神病学]