EZH2在肺癌发生发展中的研究进展  

Development of New Molecular EZH2 on Lung Cancer Invasion and Metastasis

作　　者：夏晖[1] 于长海[1] 张文[1] 张宝石[1] 赵英男[1] 

机构地区：[1]解放军总医院第一附属医院胸心外科,北京100048

出　　处：《中国肺癌杂志》2016年第2期98-101,共4页Chinese Journal of Lung Cancer

基　　金：吴阶平医学基金会临床科研专项基金(No.320.6750.14312)资助~~

摘　　要：肺癌是最常见的恶性肿瘤之一,严重威胁人类生命和健康。筛选合适的靶点是肺癌基因治疗的首要因素。研究EZH2与肺癌发生、发展的分子机制,阐明其信号调控网络,探寻新的治疗靶点和策略,将为筛选临床治疗新靶点提供重要理论支持和实验依据,可以提高肺癌患者生存率、改善生存质量,具有重要的临床应用价值和深远的社会意义。Lung cancer is a serious threat to human health malignancies upward trend in morbidity and mortality. It is hot topic to investigate the molecular mechanisms of lung cancer development and explore the new therapeutic targets. The underlying mechanism of EZH2 on lung cancer development will demonstrate the new pathway of lung cancer development, invasion and metastasis. The exploration and application of new targeted molecular will improve the survival rate and living quality of lung cancer patients in future.

关 键 词：肺肿瘤 基因治疗 EZH2 

分 类 号：R734.2[医药卫生—肿瘤]