梅毒血清学诊断的系统评价  

Systemic estimation of syphilis serologic diagnosis

作　　者：高辉[1] 裴银辉 

机构地区：[1]唐山职业技术学院临床医学系,河北唐山063000 [2]华北理工大学

出　　处：《河北联合大学学报（医学版）》2016年第1期27-29,共3页Journal of North China Coal Medical College

摘　　要：①目的系统评价快速血浆反应素试验（RPR）及酶联免疫吸附试验（ELISA）在梅毒血清学诊断中的价值。②方法运用Cochrane系统评价方法,检索中文和英文1996～2014年数据库,提取数据信息,应用RevMan 4.2软件进行系统分析。③结果共检索到相关文献92篇,评价后纳入15篇。Meta分析后显示,RPR同ELISA相比,阳性预测值OR为0.54,95%置信区间为0.39～0.74,敏感度OR为0.13,95%置信区间为0.09～0.19。④结论在梅毒血清学诊断中,ELISA法诊断价值高于RPR法。Objective Systemic assessing the value of RPR and ELISA in the serologic diagnosis of syphilis.Methods Cochrane assessment was used to perform this paper. Published materials written in Chinese and English from 1996～2014 were searched via internet database, and then analysis was performed by RevMan 4.2 software. Results 92 records were acceptable, 15 were adopted after assessment. Being treated with RevMan 4.2, it indicated that the OR of the positive predictive values of RPR to ELISA was 0.54, and the 95% CI was 0.39～0.74. The OR of the sensitivity and its 95% CI were as the following, 0.13, 0.09～0.19.Conclusion The diagnositic value of ELISA is higher than that of RPR in the confirmation of syphilis.

关 键 词：梅毒 RPR ELISA 系统评价 

分 类 号：R377.1[医药卫生—病原生物学]